845887-08-3

Basic information

• Product Name: 5-CHLOROMETHYL-3-(4-METHYLSULFANYL-PHENYL)-[1,2,4]OXADIAZOLE
• Synonyms: 5-(chloromethyl)-3-(4-(methylthio)phenyl)-1,2,4-oxadiazole;1,2,4-Oxadiazole, 5-(chloromethyl)-3-[4-(methylthio)phenyl]-
• CAS NO: 845887-08-3
• Molecular Formula: C₁₀H₉ClN₂OS
• Molecular Weight: 240.71
• Mol File: 845887-08-3.mol

Chemical Properties

• Boiling Point: 379.2°C at 760 mmHg
• Flash Point: 183.1°C
• Appearance: /
• Density: 1.36g/cm³
• Vapor Pressure: 1.3E-05mmHg at 25°C
• Refractive Index: 1.617
• CAS DataBase Reference: 5-CHLOROMETHYL-3-(4-METHYLSULFANYL-PHENYL)-[1,2,4]OXADIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-CHLOROMETHYL-3-(4-METHYLSULFANYL-PHENYL)-[1,2,4]OXADIAZOLE(845887-08-3)
• EPA Substance Registry System: 5-CHLOROMETHYL-3-(4-METHYLSULFANYL-PHENYL)-[1,2,4]OXADIAZOLE(845887-08-3)

Safety Data

• Hazardous Substances Data: 845887-08-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H9ClN2OS/c1-15-8-4-2-7(3-5-8)10-12-9(6-11)14-13-10/h2-5H,6H2,1H3

Upstream product

• 21382-98-9 p-cyanophenyl methyl sulfide 
• 500024-30-6 N-hydroxy-4-(methylthio)benzenecarboximidamide 
• 79-04-9 chloroacetyl chloride 

Downstream Products

• 1357616-90-0 5-(azidomethyl)-3-(4-(methylthio)phenyl)-1,2,4-oxadiazole 

Relevant articles and documents

Synthesis of Some Azamacrocycles Bearing 1,2,4-Oxadiazole and 1,2,3-Triazole Moieties

Abstract: A tetraazacrown ether,4,9-di(prop-2-yn-1-yl)-1,4,9,12-tetraazacyclohexadecane-2,11-dione, bearingpropargyl groups on two nitrogens was synthesized starting from1,4,9,12-tetraazacyclohexadecane-2,11-dione and subjected to 1,3-cycloadditionreactio

Reactions of 3-(p-substituted-phenyl)-5-chloromethyl-1,2,4-oxadiazoles with KCN leading to acetonitriles and alkanes via a non-reductive decyanation pathway

The present work describes an unfamiliar reaction of 5-(chloromethyl)-3-substituted-phenyl-1,2,4-oxadiazoles with KCN affording trisubstituted 1,2,4-oxadiazol-5-ylacetonitriles and their parent alkanes, namely, 1,2,3-trisubstituted-1,2,4-oxadiazol-5-ylpro

Synthesis of novel triazoles bearing 1,2,4-oxadiazole and phenylsulfonyl groups by 1,3-dipolar cycloaddition of some organic azides and their biological activities

1,3-Dipolar cycloaddition of 5-azidomethyl-3-p-substituted phenyl-1,2,4-oxadiazoles to phenyl vinyl sulfone and bismaleimide gives rise straightforwardly to 1-((3-(p-substituted) phenyl-1,2,4-oxadiazol-5-yl)methyl)-4-(phenylsulfonyl)-4,5-dihydro-1H-1,2,3-triazoles and bisdihydropyrrolo[3,4-d][1,2,3]triazole-4,6(3aH,5H)-diones. The structures of the new cycloadducts were elucidated by means of IR, NMR (1H, 13C, 2D), mass spectra, and physical characteristics (mp and Rfvalues). In addition, anticancer activities of the cycloadducts against MCF-7 cells were also investigated.

Synthesis and anti-protozoal activity of novel dihydropyrrolo[3,4-d][1,2,3] triazoles

1,2,4-Oxadiazole and 1,2,3-triazole containing heterocyclic compounds continue to gain interest in synthesis of chemical entities and exhibit various biological activities as anti-protozoal and anti-cancer agents. By using the principle of bioisosterism,