cas 84998-84-5, 2-(2,4,6-tribromophenoxy)acetic acid

Articles about 84998-84-5Total 7 be found

Synthesis and biological evaluation of some novel 2-mercaptobenzothiazoles carrying 1,3,4-oxadiazole, 1,3,4-thiadiazole and 1,2,4-triazole moieties
Several 2-mercaptobenzothiazole derivatives containing 1,3,4-oxadiazoles, 1,2,4-triazoles and 1,3,4-thiadiazoles at the second position were synthesized. Some of these synthesized compounds were evaluated for their in vivo analgesic, anti-inflammatory, acute toxicity and ulcerogenic actions. Some of the tested compounds showed significant analgesic and anti-inflammatory activities. Two of the compounds showed significant gastrointestinal protection compared to the standard drug diclofenac sodium. The compounds were also tested for their in vitro antimicrobial activity with most displaying selective activity against the Gram-negative bacteria Pseudomonas aeruginosa. In the present investigation the tested compounds did not possess antifungal activity.
Azam, M. Afzal,Suresh, Bhojraj,Kalsi, Sandip S.,Antony, A. Shinesh
scheme or table
p. 114 - 122
(2011/06/09)

Biological Evaluation of some New Nitrophenoxy/Halophenoxyaeetyl/Propionyl-2-mercaptobenzothiazoles
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Khare,Srivastava,Mukharya
p. 627 - 628
(2007/10/03)

Synthesis and screening of antimicrobial and anti-inflammatory activities of aryloxy derivatives of benzimidazoles
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Purohit,Srivastava
p. 163 - 165
(2007/10/02)

Synthesis and biological evaluation of some novel N-[2-(phenoxy/bromo/nitro/substituted-phenoxy)acetyl/propionyl] carbazole
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Jain,Srivastava
p. 775 - 776
(2007/10/02)

Design, Synthesis, and Testing of Potential Antisickling Agents. 4. Structure-Activity Relationships of Benzyloxy and Phenoxy Acids
In this paper we further establish the activity of two classes of small molecules, benzyloxy and phenoxy acids, as potent inhibitors of hemoglobin S (HbS) gelation.Structural modifications with a large number of each class confirm our earlier work that the highest activity is observed with compounds that contain dihalogenated aromatic rings with attached polar side chains.We have also found a halogenated aromatic malonic acid derivative to be quite active.Compounds reported in this paper are compared with other antigelling agents studied in our laboratory.Comments are made concerning the antigelling activity and binding sites of four derivatives and their effect on the allosteric mechanism of hemoglobin (Hb) function.
Abraham, D. J.,Kennedy, P. E.,Mehanna, A. S.,Patwa, D. C.,Williams, F. L.
p. 967 - 978
(2007/10/02)