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(R)-3-methoxydihydro-2H-pyran-4(3H)-one is a cyclic organic compound characterized by its molecular formula C6H10O3. It features a pyran ring and a methoxy group, which contribute to its versatile reactivity and unique structure. This chemical compound is widely recognized for its applications in the synthesis of natural products and pharmaceuticals, as well as its use as a flavoring agent or fragrance in consumer products. Moreover, it has demonstrated potential pharmacological properties, including antibacterial and antifungal activities, making it a valuable compound in scientific, industrial, and medicinal fields.

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  • 851916-41-1 Structure
  • Basic information

    1. Product Name: (R)-3-Methoxydihydro-2H-pyran-4(3H)-one
    2. Synonyms: (R)-3-Methoxydihydro-2H-pyran-4(3H)-one;(3R)-3-methoxyoxan-4-one
    3. CAS NO:851916-41-1
    4. Molecular Formula: C6H10O3
    5. Molecular Weight: 130.1418
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 851916-41-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 201.3±30.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.08±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (R)-3-Methoxydihydro-2H-pyran-4(3H)-one(CAS DataBase Reference)
    10. NIST Chemistry Reference: (R)-3-Methoxydihydro-2H-pyran-4(3H)-one(851916-41-1)
    11. EPA Substance Registry System: (R)-3-Methoxydihydro-2H-pyran-4(3H)-one(851916-41-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 851916-41-1(Hazardous Substances Data)

851916-41-1 Usage

Uses

Used in Pharmaceutical Synthesis:
(R)-3-methoxydihydro-2H-pyran-4(3H)-one is used as a key intermediate in the synthesis of various pharmaceuticals for its versatile reactivity and unique structure, contributing to the development of new drugs with improved therapeutic properties.
Used in Flavor and Fragrance Industry:
(R)-3-methoxydihydro-2H-pyran-4(3H)-one is used as a flavoring agent or fragrance in various consumer products, such as food, beverages, and cosmetics, due to its pleasant aroma and taste.
Used in Antibacterial Applications:
(R)-3-methoxydihydro-2H-pyran-4(3H)-one is used as an antibacterial agent, exhibiting potential activity against various bacterial strains, making it a promising candidate for the development of new antimicrobial agents.
Used in Antifungal Applications:
(R)-3-methoxydihydro-2H-pyran-4(3H)-one is used as an antifungal agent, showing potential activity against different fungal species, which can be utilized in the development of antifungal drugs and treatments.
Overall, (R)-3-methoxydihydro-2H-pyran-4(3H)-one is a multifaceted chemical compound with a wide range of applications across various industries, including pharmaceuticals, flavor and fragrance, and antimicrobial agents, highlighting its significance in modern scientific and industrial applications.

Check Digit Verification of cas no

The CAS Registry Mumber 851916-41-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,1,9,1 and 6 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 851916-41:
(8*8)+(7*5)+(6*1)+(5*9)+(4*1)+(3*6)+(2*4)+(1*1)=181
181 % 10 = 1
So 851916-41-1 is a valid CAS Registry Number.

851916-41-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (3R)-3-Methoxytetrahydro-4H-pyran-4-one

1.2 Other means of identification

Product number -
Other names MeO-pyranone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:851916-41-1 SDS

851916-41-1Relevant articles and documents

FUSED CYCLOPENTYL ANTAGONISTS OF CCR2

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Page/Page column 48-49, (2013/10/22)

The present invention comprises compounds of Formula (I). wherein: R0, R1, R2, R3, R4, R5, and A are as defined in the specification. The invention also comprises a method of preventing, treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is type II diabetes, obesity and asthma. The invention also comprises a method of inhibiting CCR2 activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula (I)

CHEMOKINE RECEPTOR ANTAGONISTS

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Page/Page column 64-65, (2013/10/22)

Disclosed herein are chemokine receptor antagonists of formula (I) wherein R1, R2, and R3 are as defined in the specification. Compositions comprising such compounds; and methods for treating conditions and disorders using

CHEMOKINE RECEPTOR ANTAGONISTS

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Paragraph 0274-0277, (2013/10/08)

Disclosed herein are chemokine receptor antagonists of formula (I) wherein R1, R2, and R3 are as defined in the specification. Compositions comprising such compounds; and methods for treating conditions and disorders using

AMINOCYCLOPENTYL PYRIDOPYRAZINONE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY

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Page/Page column 30, (2010/11/27)

Compounds of Formula I and Formula II (wherein A, E, j, k, m, n, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R15, R16, R17, R18, R19, R24, R25, R26, R27, R28, R29, R30, R31, R32, R33, R34, X, Y and Z are as defined herein) which are modulators of chemokine receptor activity and are useful in the prevention or treatment of certain inflammatory and immunoregulatory disorders and diseases, allergic diseases, atopic conditions including allergic rhinitis, dermatitis, conjunctivitis, and asthma, as well as autoimmune pathologies such as rheumatoid arthritis and atherosclerosis. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which chemokine receptors are involved.

CCR-2 ANTAGONIST SALT

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Page/Page column 24, (2008/06/13)

The present invention provides an efficient synthesis for the preparation of ((1R,3S)-3-isopropyl-3-{[3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl]carbonyl}cyclopentyl)[(3S,4S)-3-m ethoxytetrahydro-2H-pyran-4-yl]amine and its succinate salt.

PROCESS FOR THE PREPARATION OF CCR-2 ANTAGONIST

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Page/Page column 12; 24, (2010/02/11)

The present invention provides an efficient synthesis for the preparation of ((1R,3S)-3-isopropyl-3- {[3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl]carbonyl} cyclopentyl)[(3S,4S)-3-m ethoxytetrahydro- 2H-pyran-4-yl]amine and its succinate sal

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