852110-51-1

Basic information

• Product Name: (7-BroMo-2,3-dihydrobenzofuran-2-yl)Methanol
• Synonyms: (7-BroMo-2,3-dihydrobenzofuran-2-yl)Methanol;7-bromo-2-hydroxymethyl-2,3-dihydrobenzo[b]furan
• CAS NO: 852110-51-1
• Molecular Formula: C₉H₉BrO₂
• Molecular Weight: 229.07056
• Mol File: 852110-51-1.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (7-BroMo-2,3-dihydrobenzofuran-2-yl)Methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (7-BroMo-2,3-dihydrobenzofuran-2-yl)Methanol(852110-51-1)
• EPA Substance Registry System: (7-BroMo-2,3-dihydrobenzofuran-2-yl)Methanol(852110-51-1)

Safety Data

• Hazardous Substances Data: 852110-51-1(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
(7-Bromo-2,3-dihydrobenzofuran-2-yl)Methanol is utilized as a building block in organic synthesis for the creation of various organic molecules. Its unique structure and reactivity make it a valuable intermediate in the synthesis of complex organic compounds.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (7-Bromo-2,3-dihydrobenzofuran-2-yl)Methanol is employed as a key component in the synthesis of pharmaceuticals. Its potential biological activity and the versatility of its chemical structure allow for the development of new drugs with specific therapeutic targets.
Used in Drug Discovery:
(7-Bromo-2,3-dihydrobenzofuran-2-yl)Methanol is of interest to researchers in drug discovery due to its potential to exhibit biological activity. (7-BroMo-2,3-dihydrobenzofuran-2-yl)Methanol's unique structural features and the possibility of its interaction with biological systems make it a candidate for further exploration and development as a pharmaceutical agent.
Used in Chemical Research:
(7-BroMo-2,3-dihydrobenzofuran-2-yl)Methanol is also used in chemical research to study the properties and reactivity of bromine-substituted benzofuran derivatives. Understanding these characteristics can lead to the discovery of new synthetic pathways and applications in various scientific and technological fields.

Upstream product

• 60333-75-7 O-allyl-2-bromophenol 
• 17269-81-7 2-bromo-6-(2-propenyl)phenol 
• 95-56-7 2-hydroxybromobenzene 

Downstream Products

• 852110-52-2 (7-bromo-2,3-dihydro-1-benzofuran-2-yl)methyl-4-methylbenzenesulfonate 

Relevant articles and documents

Green Organocatalytic Synthesis of Dihydrobenzofurans by Oxidation-Cyclization of Allylphenols

A green and cheap protocol for the synthesis of dihydrobenzofurans via an organocatalytic oxidation of o -allylphenols is presented. The use of 2,2,2-trifluoroacetophenone and H 2 O 2 as the oxidation system, leads to a highly useful synthetic method, where a variety of substituted o -allylphenols were cyclized in high yields..

Synthesis and biological evaluation of novel n-[(7-pyridin-4-yl-2, 3-dihydro-benzofuran-2-yl) methyl]-(4-methyl-1, 2, 3-thiadiazole-5-yl) formamide as a potent immunosuppressant agent

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MACROCYCLIC GHRELIN RECEPTOR MODULATORS AND METHODS OF USING THE SAME

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Azidosubstituted arylboronic acids: Synthesis and Suzuki-Miyaura cross-coupling reactions

Arylboronic acids having a remote azido group were prepared from the corresponding azidosubstituted aryl bromides via lithiation and treatment with trialkyl borates. Preparative yields were achieved when the starting aryl bromides possessed ortho-alkoxy groups, which would stabilize the intermediate aryllithium species. Conventional Suzuki cross-coupling of the arylboronic acids proceeded generally well with retention of azido group; however, sometimes azidomethyl fragment underwent oxidative transformation into a nitrile.

DIHYDROBENZOFURAN COMPOUNDS AND USES THEREOF

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DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS

Compounds of Formula (I) or pharmaceutically acceptable salts thereof are provided: Formula (I) which are agonists or partial agonists of the 2C subtype of brain serotonin receptors. The compounds, and compositions containing the compounds, can be used to treat a variety of central nervous system disorders such as schizophrenia.