852238-97-2

Basic information

• Product Name: S-NICOTINE-5-CARBOXALDEHYDE
• Synonyms: S-NICOTINE-5-CARBOXALDEHYDE;5-[(2S)-1-Methyl-2-pyrrolidinyl]-3-pyridinecarboxaldehyde
• CAS NO: 852238-97-2
• Molecular Formula: C11H14N2O
• Molecular Weight: 190.245
• Product Categories: Nicotine Derivatives;Chiral Reagents;Heterocycles;Mutagenesis Research Chemicals
• Mol File: 852238-97-2.mol

Chemical Properties

• Appearance: /
• Storage Temp.: -20°C Freezer
• CAS DataBase Reference: S-NICOTINE-5-CARBOXALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: S-NICOTINE-5-CARBOXALDEHYDE(852238-97-2)
• EPA Substance Registry System: S-NICOTINE-5-CARBOXALDEHYDE(852238-97-2)

Safety Data

• Hazardous Substances Data: 852238-97-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
S-NICOTINE-5-CARBOXALDEHYDE is used as a pharmaceutical agent for its ability to modulate nicotinic acetylcholine receptors. This makes it a potential candidate for the development of drugs targeting neurological disorders and conditions related to the central nervous system.
Used in Neurological Research:
In the field of neurological research, S-NICOTINE-5-CARBOXALDEHYDE serves as a valuable tool for studying the function and mechanisms of nicotinic acetylcholine receptors. Understanding these receptors' role in various cognitive processes and neurological conditions can lead to the discovery of new therapeutic approaches and treatments.
Used in Smoking Cessation Aids:
S-NICOTINE-5-CARBOXALDEHYDE is used as an ingredient in smoking cessation aids, such as nicotine replacement therapies. Its ability to modulate nicotinic acetylcholine receptors helps in reducing nicotine cravings and withdrawal symptoms, thereby assisting individuals in quitting smoking.
Used in Agrochemical Industry:
In the agrochemical industry, S-NICOTINE-5-CARBOXALDEHYDE can be utilized as an active ingredient in pesticides or insecticides. Its interaction with nicotinic acetylcholine receptors in insects can lead to their paralysis and death, making it a potential candidate for pest control solutions.
Overall, S-NICOTINE-5-CARBOXALDEHYDE's diverse applications across various industries highlight its significance in both therapeutic and non-therapeutic domains. Its ability to modulate nicotinic acetylcholine receptors makes it a promising compound for further research and development in multiple fields.

Upstream product

• 852238-96-1 (S)-5-(1-methylpyrrolidin-2-yl)-1,4-dihydropyridine-3-carbaldehyde 
• 54-11-5 nicotin 
• 852238-91-6 (S)-3-(1-methylpyrrolidin-2-yl)-1,4-bis-trimethylsilanyl-1,4-dihydropyridine 
• 852238-94-9 3-(1-methylpyrrolidin-2-yl)-4H-pyridine-1-carboxylic acid methyl ester 
• 852238-95-0 (S)-3-formyl-5-(1-methylpyrrolidin-2-yl)-4H-pyridine-1-carboxylic acid methyl ester 

Downstream Products

• 179120-92-4 altinicline 

Relevant articles and documents

A six-step synthesis of (S)-5-ethenyl-3-(1-methyl-2-pyrrolidinyl)pyridine (SIB-1508Y) from (S)-nicotine

The anti-Parkinson's agent SIB-1508Y was prepared in six steps from (S)-nicotine in 20% overall yield. The strategy involves a regioselective formylation at C-5 of a 1,4-dihydronicotine intermediate.

Synthesis of nicotine derivatives from nicotine

Methods of synthesizing nicotine analogs and derivatives are described. In some embodiments the methods utilize an alkyl or aryl silyl-substituted nicotine analog intermediate. Intermediates useful for the synthesis of nicotine and nicotine analogs are al