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tert-butyl 4-(1-fluoro-2-hydroxyethyl)piperidine-1-carboxylate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 858342-22-0 Structure
  • Basic information

    1. Product Name: tert-butyl 4-(1-fluoro-2-hydroxyethyl)piperidine-1-carboxylate
    2. Synonyms: tert-butyl 4-(1-fluoro-2-hydroxyethyl)piperidine-1-carboxylate;tert-Butyl 4-[(1R)-1-fluoro-2-hydroxyethyl]piperidine-1-carboxylat;tert-butyl 4-[(1R)-1-fluoro-2-hydroxyethyl]piperidine-1-carboxylate
    3. CAS NO:858342-22-0
    4. Molecular Formula: C12H22FNO3
    5. Molecular Weight: 247.3063832
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 858342-22-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: tert-butyl 4-(1-fluoro-2-hydroxyethyl)piperidine-1-carboxylate(CAS DataBase Reference)
    10. NIST Chemistry Reference: tert-butyl 4-(1-fluoro-2-hydroxyethyl)piperidine-1-carboxylate(858342-22-0)
    11. EPA Substance Registry System: tert-butyl 4-(1-fluoro-2-hydroxyethyl)piperidine-1-carboxylate(858342-22-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 858342-22-0(Hazardous Substances Data)

858342-22-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 858342-22-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,8,3,4 and 2 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 858342-22:
(8*8)+(7*5)+(6*8)+(5*3)+(4*4)+(3*2)+(2*2)+(1*2)=190
190 % 10 = 0
So 858342-22-0 is a valid CAS Registry Number.

858342-22-0Downstream Products

858342-22-0Relevant articles and documents

N-SULFONYLATED PYRAZOLO[3,4-B]PYRIDIN-6-CARBOXAMIDES AND METHOD OF USE

-

, (2017/04/23)

The present invention provides for compounds of formula (I) wherein R1, R2, R3, R4, R5, and R6 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions mediated and modulated by CFTR, including cystic fibrosis, Sj?gren's syndrome, pancreatic insufficiency, chronic obstructive lung disease, and chronic obstructive airway disease. Also provided are pharmaceutical compositions comprised of one or more compounds of formula (I).

SUBSTITUTED PYRAZOLO[3,4-b]PYRIDIN-6-CARBOXYLIC ACIDS AND METHOD OF USE

-

, (2017/05/14)

The present invention provides for compounds of formula (I) wherein R1, R2, R3, and R4 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions mediated and modulated by CFTR, including cystic fibrosis, Sj?gren's syndrome, pancreatic insufficiency, chronic obstructive lung disease, and chronic obstructive airway disease. Also provided are pharmaceutical compositions comprised of one or more compounds of formula (I).

Design and evaluation of a 2-(2,3,6-trifluorophenyl)acetamide derivative as an agonist of the GPR119 receptor

Mascitti, Vincent,Stevens, Benjamin D.,Choi, Chulho,McClure, Kim F.,Guimar?es, Cristiano R.W.,Farley, Kathleen A.,Munchhof, Michael J.,Robinson, Ralph P.,Futatsugi, Kentaro,Lavergne, Sophie Y.,Lefker, Bruce A.,Cornelius, Peter,Bonin, Paul D.,Kalgutkar, Amit S.,Sharma, Raman,Chen, Yue

, p. 1306 - 1309 (2011/04/16)

The design and synthesis of a GPR119 agonist bearing a 2-(2,3,6- trifluorophenyl)acetamide group is described. The design capitalized on the conformational restriction found in N-β-fluoroethylamide derivatives to help maintain good levels of potency while

Enantioselective alpha-fluorination of aldehydes using chiral organic catalysts

-

Page/Page column 9; 10, (2008/06/13)

Nonmetallic, chiral organic catalysts are used to catalyze enantioselective fluorination of enolizable aldehydes. Reaction systems composed of an enolizable aldehyde, an electrophilic fluorination reagent, and a nonmetallic chiral catalyst in the form of

Enantioselective organocatalytic α-fluorination of aldehydes

Beeson, Teresa D.,MacMillan, David W. C.

, p. 8826 - 8828 (2007/10/03)

The first direct enantioselective catalytic α-fluorination of aldehydes has been accomplished. The use of enamine catalysis has provided a new organocatalytic strategy for the enantioselective fluorination of aldehydes to generate α-fluoro aldehydes, an i

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