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N'-(2,3-dihydroxybenzylidene)benzohydrazide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

858647-72-0

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858647-72-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 858647-72-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,8,6,4 and 7 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 858647-72:
(8*8)+(7*5)+(6*8)+(5*6)+(4*4)+(3*7)+(2*7)+(1*2)=230
230 % 10 = 0
So 858647-72-0 is a valid CAS Registry Number.

858647-72-0Relevant articles and documents

Syntheses, characterization, and crystal structures of few dioxomolybdenum(VI) complexes incorporating tridentate hydrazones

Nandy, Madhusudan,Shit, Shyamapada,Rizzoli, Corrado,Pilet, Guillaume,Mitra, Samiran

, p. 63 - 72 (2015)

Three new cis-dioxomolybdenum(VI) complexes, [MoO2(L1)(CH3OH)] (1), [MoO2(L2)(CH3OH)] (2), and [MoO2(L3)(CH3OH)] (3) have been synthesized using three diffe

2,3,4-Trihydroxybenzyl-hydrazide analogues as novel potent coxsackievirus B3 3C protease inhibitors

Kim, Bo-Kyoung,Ko, Hyojin,Jeon, Eun-Seok,Ju, Eun-Seon,Jeong, Lak Shin,Kim, Yong-Chul

, p. 202 - 216 (2016/05/24)

Human coxsackievirus B3 (CVB3) 3C protease plays an essential role in the viral replication of CVB3, which is a non-enveloped and positive single-stranded RNA virus belonging to Picornaviridae family, causing acute viral myocarditis mainly in children. During optimization based on SAR studies of benserazide (3), which was reported as a novel anti-CVB3 3Cpro agent from a screening of compound libraries, the 2,3,4-trihydroxybenzyl moiety of 3 was identified as a key pharmacophore for inhibitory activity against CVB3 3Cpro. Further optimization was performed by the introduction of various aryl-alkyl substituted hydrazide moieties instead of the serine moiety of 3. Among the optimized compounds, 11Q, a 4-hydroxyphenylpentanehydrazide derivative, showed the most potent inhibitory activity (IC50 Combining double low line 0.07 μM). Enzyme kinetics studies indicated that 11Q exhibited a mixed inhibitory mechanism of action. The antiviral activity against CVB3 was confirmed using the further derived analogue (14b) with more cell permeable valeryl ester group at the 2,3,4-trihydroxy moiety.

Design, synthesis and in vitro antimalarial activity of an acylhydrazone library

Melnyk, Patricia,Leroux, Virginie,Sergheraert, Christian,Grellier, Philippe

, p. 31 - 35 (2007/10/03)

A library of acylhydrazone iron chelators was synthesized and tested for its ability to inhibit the growth of a chloroquine-resistant strain of Plasmodium falciparum. Some of these new compounds are significantly more active than desferrioxamine DFO, the

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