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54-85-3

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Product FOB Price Min.Order Supply Ability Supplier
Isonicotinylhydrazide China mainland supplier
Cas No: 54-85-3
USD $ 1.2-15.0 / Kilogram 1 Kilogram 1000 Kilogram/Week SHANGHAI KAIWODUN BIOCHEMICAL CO.,LTD Contact Supplier
Isoniazid
Cas No: 54-85-3
USD $ 1.0-2.0 / Metric Ton 1 Metric Ton 100 Metric Ton/Week Hebei yanxi chemical co.,LTD. Contact Supplier
CAS:54-85-3 Isoniazid
Cas No: 54-85-3
No Data 1 Kilogram 100 Kilogram/Week Kono Chem Co.,Ltd Contact Supplier
High purity Various Specifications Isonicotinic acid hydrazide CAS:54-85-3
Cas No: 54-85-3
USD $ 100.0-500.0 / Gram 1 Gram 99999 Gram/Year Hangzhou Dingyan Chem Co., Ltd Contact Supplier
High quality Isoniazid Cas 54-85-3 with best price and good service
Cas No: 54-85-3
USD $ 23.0-25.0 / Kilogram 25 Kilogram 125 Metric Ton/Year Wuhan Fortuna Chemical Co.,Ltd Contact Supplier
Good quality Isoniazid//54-85-3
Cas No: 54-85-3
No Data 1 Kilogram 10 Metric Ton/Month Hefei TNJ chemical industry co.,ltd Contact Supplier
High quality Isoniazid supplier in China
Cas No: 54-85-3
No Data No Data No Data Simagchem Corporation Contact Supplier
Isoniazid
Cas No: 54-85-3
No Data No Data No Data Chemwill Asia Co., Ltd. Contact Supplier
High purity Isoniazid 98% TOP1 supplier in China
Cas No: 54-85-3
USD $ 1.0-2.0 / Gram 100 Gram 100 Metric Ton/Month Hangzhou Dayangchem Co., Ltd. Contact Supplier
Isoniazid
Cas No: 54-85-3
No Data 1 Kilogram 100 Kilogram/Month HENAN SUNLAKE ENTERPRISE CORPORATION Contact Supplier

54-85-3 Usage

Chemical Properties

white crystalline powder

Uses

Antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Sele ctively induces expression of CYP2E1. Reversibly inhibits CYP2C19 and CYP3A4 activities, and mechanistically inactivates CYP1A2, CYP2A6, CYP2C19 and CYP3A4 at clinically relevant concentrations. Antib acterial (tuberculostatic).

Reactivity Profile

Isoniazid is incompatible with chloral, aldehydes, iodine, hypochlorites and ferric salts. Isoniazid is also incompatible with oxidizers. Isoniazid may react with sugars and ketones. Isoniazid can react as a weak acid or a weak base. Isoniazid can be decomposed by oxidative and reductive reactions.

Purification Methods

Crystallise isoniazide from 95% EtOH and dry it in a vacuum. [Beilstein 22 III/IV 545, 22/2 V 219.]

Uses

For the treatment of all forms of tuberculosis in which organisms are susceptible.

General Description

Odorless colorless or white crystals or white crystalline powder. Taste is slightly sweet at first and then bitter. pH (1% aqueous solution) 5.5-6.5. pH (5% aqueous solution) 6-8.

Brand name

Inh (Novartis); Nydrazid (Bristol-Myers Squibb); Nydrazid (Sandoz); Rimifon (Roche).

Air & Water Reactions

Sensitive to air and light. Absorbs insignificant amounts of moisture at 77°F at relative humidities up to approximately 90%. Water soluble. Dust can be explosive when suspended in air at specific concentrations.

Definition

ChEBI: A carbohydrazide obtained by formal condensation between pyridine-4-carboxylic acid and hydrazine.

Fire Hazard

Isoniazid is combustible.

Uses

antibacterial, tuberculostatic
InChI:InChI=1/C6H7N3O2/c7-9-11-6(10)5-1-3-8-4-2-5/h1-4,9H,7H2

54-85-3 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
Sigma-Aldrich (I3377)  Isoniazid  analytical standard, ≥99% (TLC) 54-85-3 I3377-250G 693.81CNY Detail
Sigma-Aldrich (I3377)  Isoniazid  analytical standard, ≥99% (TLC) 54-85-3 I3377-50G 198.90CNY Detail
Sigma-Aldrich (I3377)  Isoniazid  analytical standard, ≥99% (TLC) 54-85-3 I3377-5G 157.95CNY Detail
USP (1349706)  Isoniazid  United States Pharmacopeia (USP) Reference Standard 54-85-3 1349706-200MG 4,662.45CNY Detail
Sigma-Aldrich (I0500000)  Isoniazid  European Pharmacopoeia (EP) Reference Standard 54-85-3 I0500000 1,880.19CNY Detail
Sigma-Aldrich (75182)  Isoniazid  certified reference material, TraceCERT® 54-85-3 75182-50MG 1,547.91CNY Detail
Alfa Aesar (A10583)  Isonicotinic acid hydrazide, 98+%    54-85-3 1000g 1094.0CNY Detail
Alfa Aesar (A10583)  Isonicotinic acid hydrazide, 98+%    54-85-3 500g 587.0CNY Detail
Alfa Aesar (A10583)  Isonicotinic acid hydrazide, 98+%    54-85-3 100g 157.0CNY Detail
Alfa Aesar (A10583)  Isonicotinic acid hydrazide, 98+%    54-85-3 50g 106.0CNY Detail
TCI America (I0138)  Isonicotinic Acid Hydrazide  >98.0%(HPLC)(T) 54-85-3 500g 1,290.00CNY Detail
TCI America (I0138)  Isonicotinic Acid Hydrazide  >98.0%(HPLC)(T) 54-85-3 100g 410.00CNY Detail

54-85-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name isoniazide

1.2 Other means of identification

Product number -
Other names HIA

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:54-85-3 SDS

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