859155-89-8

Basic information

• Product Name: 3-CARBOXYMETHYL-MORPHOLINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER
• Synonyms: 4-BOC-MORPHOLINE-3-ACETIC ACID;4-N-BOC-MORPHOLINE-3-ACETIC ACID;3-CARBOXYMETHYL-MORPHOLINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER;N-Boc-3-morpholineacetic acid;4-Boc-3-carboxymethylmorpholine;3-Morpholineacetic acid, 4-[(1,1-dimethylethoxy)carbonyl]-;[4-(tert-butoxycarbonyl)morpholin-3-yl]acetic acid;4-Boc-3-morpholineacetic acid
• CAS NO: 859155-89-8
• Molecular Formula: C11H19NO5
• Molecular Weight: 245.27
• EINECS: 200-589-5
• Product Categories: Heterocycles series;pharmacetical
• Mol File: 859155-89-8.mol

Chemical Properties

• Boiling Point: 388.244 °C at 760 mmHg
• Flash Point: 188.603 °C
• Appearance: /
• Density: 1.18 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.482
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-CARBOXYMETHYL-MORPHOLINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CARBOXYMETHYL-MORPHOLINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER(859155-89-8)
• EPA Substance Registry System: 3-CARBOXYMETHYL-MORPHOLINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER(859155-89-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 859155-89-8(Hazardous Substances Data)

Usage

Uses

4-N-Boc-Morpholine-3-Acetic Acid is a useful research chemical.

InChI:InChI=1/C11H19NO5/c1-11(2,3)17-10(15)12-4-5-16-7-8(12)6-9(13)14/h8H,4-7H2,1-3H3,(H,13,14)

Upstream product

• 81684-84-6 ethyl 2-(morpholin-3-yl)acetate 
• 761460-02-0 tert-Butyl 3-(2-ethoxy-2-oxoethyl)morpholine-4-carboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 1784401-31-5 tert-butyl 3-(2-hydroxyethyl)morpholine-4-carboxylate 
• 1398397-37-9 methyl 3-(3-(2-(((R)-1-(naphthalen-1-yl)ethyl)amino)ethyl)morpholino)-5-(trifluoromethyl)benzoate 
• 1398397-43-7 methyl 3-(3-(2-(((R)-1-(naphthalen-1-yl)ethyl)amino)ethyl)morpholino)-5-(trifluoromethyl)benzoate 
• 1373273-10-9 1-(4-benzyl-1,4-diazepan-1-yl)-2-[4-(propan-2-yl)morpholin-3-yl]ethan-1-one 
• 1373273-09-6 tert-butyl 3-[2-(4-benzyl-1,4-diazepan-1-yl)-2-oxoethyl]morpholine-4-carboxylate 

Relevant articles and documents

SUBSTITUTED MORPHOLINES AS MODULATORS FOR THE CALCIUM SENSING RECEPTOR

Compounds of Formula (I) along with processes for their preparation that are useful for treating, managing and/or lessening the diseases, disorders, syndromes or conditions associated with the modulation of calcium sensing (CaSR) receptors. Methods of treating, managing and/or lessening the diseases, disorders, syndromes or conditions associated with the modulation of calcium sensing (CaSR) receptors of Formula (I).

SUBSTITUTED MORPHOLINES AS MODULATORS FOR THE CALCIUM SENSING RECEPTOR

Compounds of Formula (I) along with processes for their preparation that are useful for treating, managing and/or lessening the diseases, disorders, syndromes or conditions associated with the modulation of calcium sensing (Ca SR) receptors. Methods of treating, managing and/or lessening the diseases, disorders, syndromes or conditions associated with the modulation of calcium sensing (Ca SR) receptors of Formula (I).

Process for producing enantiopure beta-amino acid derivatives, and enantiopure beta-amino acid derivatives

Process for producing enantiopure β-amino acid derivatives corresponding to general formula (I) R1-NZ-CHR2—CH2—COOR3 (I) in which R1 and R2 independently denote organic residues optionally forming a cyclic substituent, R3 denotes H or an organic residue, and Z represents H or an amino function-protecting group, comprising a step in which a mixture of enantiomers of a compound corresponding to general formula (II) R1-NZ-CHR2—CH2—COOR4 (II) in which R1, R2 and Z are as defined for formula (I), and R4 is an organic residue, is subjected to hydrolysis in the presence of a lipase.