859940-73-1Relevant articles and documents
PYRIMIDINE OR PYRIDOPYRIDONE COMPOUND AND APPLICATION THEREOF
-
Paragraph 0046; 0058, (2018/11/21)
The present invention discloses a pyrimidine or pyridopyridone compound as shown in formula (I) and an application thereof relating to the technical field of medicament preparation. The compound can selectively suppress cyclin-dependent kinases (Cdks) CDK
Imidazole derivative used as antiviral agent and use thereof in preparation of medicament
-
Paragraph 0262; 0265; 0266, (2016/10/07)
Disclosed are an antiviral compound and a use thereof in the preparation of a medicament for the treatment of virus infections. Specifically, the present invention relates an imidazole derivative for treating respiratory syncytial virus infection.
NOVEL 1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE DERIVATIVES SUBSTITUTED WITH HETEROCYCLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS
-
Paragraph 0826; 0828; 0829, (2015/04/28)
The present invention is concerned with novel 1,3-dihydro-2H-benzimidazol-2-one derivatives substituted with heterocycles having formula (I) stereoisomeric forms thereof, and the pharmaceutically acceptable addition salts, and the solvates thereof, wherei
SPIRO UREA COMPOUNDS AS RSV ANTIVIRAL COMPOUNDS
-
Page/Page column 31; 32, (2015/11/09)
The invention concerns novel substituted spiro urea azetidinyl or piperidinyl compounds of formula (I) having antiviral activity, in particular, having an inhibitory activity on the replication of the respiratory syncytial virus (RSV). The invention furth
RSV ANTIVIRAL COMPOUNDS
-
Page/Page column 48; 49, (2014/05/07)
Inhibitors of RSV replication of formula RI including stereochemically isomeric forms, and salts or solvates thereof, wherein R22, W, Q, V, Z p,s,and Het have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other RSV inhibitors, in RSV therapy.
QUINOXALINONES AND DIHYDROQUINOXALINONES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS
-
Page/Page column 41; 42, (2014/08/07)
Quinoxalinones and dihydroquinoxalinones having inhibitory activity on RSV replication and having the formula (I) including addition salts, and stereochemically isomeric forms thereof; compositions containing these compounds as active ingredient and processes for preparing these compounds and compositions.
NOVEL COMPOUNDS
-
Paragraph 0471; 0472; 0473, (2014/06/25)
Compounds of formula (I) defined herein exhibit human neutrophil elastase inhibitory properties and are useful for treating diseases and conditions in which HNE is implicated.
NOVEL COMPOUNDS
-
Page/Page column 67, (2014/07/08)
This invention relates to heterocyclic compounds, which are pyrimidinone derivatives having human neutrophil elastase inhibitory properties, and their use in therapy.
HETEROCYCLIC INHIBITORS OF GLUTAMINASE
-
Page/Page column 128, (2013/06/06)
The invention relates to the heterocyclic compounds of Formula (I) as defined further herein, and pharmaceutical preparations thereof. The invention further relates to methods of treating cancer, immunological or neurological diseases using the heterocyclic compounds of the invention.
INDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS
-
Paragraph 0092; 0094-0095, (2013/10/22)
Indoles having inhibitory activity on RSV replication and having the formula I the prodrugs, N-oxides, addition salts, quaternary amines, metal complexes and stereochemically isomeric forms thereof; compositions containing these compounds as active ingredient and processes for preparing these compounds and compositions.