Valuable synthetic building blocks: Useful 2-substituted 5-amino-pyrimidines from a stable precursor
An efficient large-scale synthesis of 5-aminopyrimidine derivatives is described. The dihexafluorophosphate salt of a vinamidinium cation important in 5-aminopyrimidine synthesis has been prepared as a stable, easily purified intermediate. It has been use
Dousson, Cyril B.,Heron, Nicola M.,Hill, George B.