865663-96-3

Basic information

• Product Name: 2-Chloro-3-(difluoroMethyl)pyridine
• Synonyms: 2-Chloro-3-(difluoroMethyl)pyridine;2-Chloro-3-(difluoromethyl)pyridine 95%;2-Chloro-alpha,alpha-difluoro-3-picoline
• CAS NO: 865663-96-3
• Molecular Formula: C6H4ClF2N
• Molecular Weight: 163.5524664
• Mol File: 865663-96-3.mol

Chemical Properties

• Flash Point: 80℃
• Appearance: /
• Density: 1.388
• Refractive Index: 1.491
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-Chloro-3-(difluoroMethyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-3-(difluoroMethyl)pyridine(865663-96-3)
• EPA Substance Registry System: 2-Chloro-3-(difluoroMethyl)pyridine(865663-96-3)

Safety Data

• Hazard Codes: T
• Statements: 25-36/37/38
• Safety Statements: 26-45
• RIDADR: UN 2810 6.1 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 865663-96-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Chloro-3-(difluoroMethyl)pyridine is utilized as a key intermediate in the synthesis of pharmaceuticals, contributing to the development of new drugs with potential therapeutic applications. Its unique structural features allow for the creation of diverse chemical entities that can target specific biological pathways or receptors.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Chloro-3-(difluoroMethyl)pyridine serves as an essential building block for the production of various agrochemicals, such as pesticides and herbicides. Its incorporation into these compounds can enhance their effectiveness in controlling pests and weeds, thereby improving crop yields and food security.
Used in Chemical Compound Production:
2-Chloro-3-(difluoroMethyl)pyridine has been studied for its potential as a versatile building block in the synthesis of other chemical compounds. Its presence in these compounds can impart specific properties or functionalities, broadening the scope of applications in various industries.

Upstream product

• 36404-88-3 2-chloro-3-carbaldehydepyridine 
• 109-09-1 2-chloropyridine 

Downstream Products

• 1620575-09-8 3-(difluoromethyl)-N-(diphenylmethylene)pyridin-2-amine 
• 878804-93-4 3-(difluoromethyl)pyridin-2-amine 

Relevant articles and documents

FUSED BICYLIC PYRIDINE COMPOUNDS AND THEIR USE AS AMPA RECEPTOR MODULATORS

Provided herein are compounds of Formula (I), and pharmaceutically acceptable salts, N-oxides, or solvates thereof, Also provided herein are pharmaceutical compositions comprising compounds of Formula (I) and methods of using compounds of Formula (I).

3-SUBSTITUTED PYRAZOLES AND USE AS DLK INHIBITORS

The present invention provides for compounds of Formula (I) and various embodiments thereof, and compositions comprising compounds of Formula (I) and various embodiments thereof. (I) In compounds of Formula I, the groups R1, R2, R3, R4, R5, R6 and R7 have the meaning as described herein. The present invention also provides for methods of using compounds of Formula I and compositions comprising compounds of Formula (I) as DLK inhibitors and for treating neurodegeneration diseases and disorders.

8-AZABICYCLO[3.2.1]OCTANE-8-CARBOXAMIDE DERIVATIVE

Disclosed is a compound represented by formula (1) or a pharmacologically acceptable salt thereof (In the formula, A represents a group that is represented by formula (A-1); R1a and R1b may be the same or different and each independently represents a C1-6 alkyl group which may be substituted by one to three halogen atoms; m and n each independently represents an integer of 0-5; X1 represents a hydroxyl group or an aminocarbonyl group; Z1 represents a single bond or the like; and R2 represents an optionally substituted C1-6 alkyl group, an optionally substituted C6-10 aryl group or the like.)

NOVEL SUBSTITUTED IMIDAZOLE DERIVATIVES

The present invention relates to a compound represented by Formula [I] or a pharmaceutically acceptable salt or ester thereof: wherein: X1, X2, X3, and X4, which may be identical or different, are each C or N, provided that none to two of X1, X2, X3, and X4 is/are N; Y is CH or N; R1, R1', R2, R2', R3, R3', R4, and R4', which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the like; R5 is a hydrogen atom or a methyl group; R6 and R7, which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the like; R8 and R8', which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the like; R9 is an aryl group or a heteroaryl group which may be substituted; and n is an integer from 1 to 3, and a PLK1 inhibitor or an anticancer agent containing the same.