870721-53-2 Usage
Uses
Used in Pharmaceutical Industry:
TRANS-1-BOC-2-PHENYL-PYRROLIDINE-3-CARBOXYLIC ACID is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure and Boc protecting group make it an essential component in the development of new drugs with improved efficacy and selectivity.
Used in Agrochemical Industry:
In the agrochemical sector, TRANS-1-BOC-2-PHENYL-PYRROLIDINE-3-CARBOXYLIC ACID serves as a crucial intermediate for the preparation of agrochemicals. Its incorporation into the molecular structures of these compounds contributes to their effectiveness in pest control and crop protection.
Used as a Chiral Building Block:
TRANS-1-BOC-2-PHENYL-PYRROLIDINE-3-CARBOXYLIC ACID is utilized as a chiral building block in the synthesis of complex molecules. Its asymmetric center and Boc-protected nitrogen atom provide a foundation for constructing enantiomerically pure compounds, which are vital in various chemical and biological applications.
Storage and Handling:
Due to its reactivity and potential for degradation, TRANS-1-BOC-2-PHENYL-PYRROLIDINE-3-CARBOXYLIC ACID is typically handled and stored under controlled conditions. These measures ensure the preservation of its structural integrity and prevent undesired reactions, maintaining its utility in various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 870721-53-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,0,7,2 and 1 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 870721-53:
(8*8)+(7*7)+(6*0)+(5*7)+(4*2)+(3*1)+(2*5)+(1*3)=172
172 % 10 = 2
So 870721-53-2 is a valid CAS Registry Number.
870721-53-2Relevant articles and documents
SUBSTITUTED PYRROLIDINE AMIDES V
-
, (2021/01/22)
The invention relates to compounds according to general formula (I), which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.
Diastereoselective access to enantiomerically pure cis-2,3-disubstituted pyrrolidines
Delaye, Pierre-Olivier,Pradhan, Tanin K.,Lambert, Emilie,Vasse, Jean-Luc,Szymoniak, Jan
experimental part, p. 3395 - 3406 (2010/08/20)
A straightforward access to enantiomerically pure 2,3-disubstituted pyrrolidines is reported that involves diastereoselective allylation of (R)-phenylglycinol-derived imines and a sequential hydrozirconation-cyclization. A number of pyrrolidine derivatives bearing aryl, heteroaryl, alkyl and alkenyl groups have been prepared in this way. Such compounds are useful building blocks in the synthesis of molecules of biological interest, as illustrated by the syntheses of proline derivatives and the naturally occurring alkaloid (-)-isoretronecanol.
3-AMINO-2-PHENYLPYRROLIDINE DERIVATIVES
-
Page/Page column 78, (2010/02/14)
3-amino-2-phenylpyrrolidine compounds useful as NK-1 antagonists, with pharmaceutical compositions and methods of treatment comprising same, are disclosed.
