871266-82-9 Usage
Uses
Used in Pharmaceutical Industry:
(7-CHLOROTHIAZOLO[5,4-D]PYRIMIDIN-2-YL)-(3-TRIFLUOROMETHYLPHENYL)AMINE is used as a potential drug candidate for the treatment of various diseases. Its unique chemical structure and biological activity make it a promising compound for the development of new therapeutics.
Used in Research and Development:
In the field of medicinal chemistry, (7-CHLOROTHIAZOLO[5,4-D]PYRIMIDIN-2-YL)-(3-TRIFLUOROMETHYLPHENYL)AMINE is used as a research compound to study its interactions with biological targets and to understand its potential therapeutic effects. This knowledge can help in the design and development of new drugs with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 871266-82-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,1,2,6 and 6 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 871266-82:
(8*8)+(7*7)+(6*1)+(5*2)+(4*6)+(3*6)+(2*8)+(1*2)=189
189 % 10 = 9
So 871266-82-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H6ClF3N4S/c13-9-8-10(18-5-17-9)21-11(20-8)19-7-3-1-2-6(4-7)12(14,15)16/h1-5H,(H,19,20)
871266-82-9Relevant articles and documents
Identification and synthesis of 2,7-diamino-thiazolo[5,4-d]pyrimidine derivatives as TRPV1 antagonists
Lebsack, Alec D.,Branstetter, Bryan J.,Hack, Michael D.,Xiao, Wei,Peterson, Matthew L.,Nasser, Nadia,Maher, Michael P.,Ao, Hong,Bhattacharya, Anindya,Kansagara, Mena,Scott, Brian P.,Luo, Lin,Rynberg, Raymond,Rizzolio, Michele,Chaplan, Sandra R.,Wickenden, Alan D.,Guy Breitenbucher
scheme or table, p. 40 - 46 (2009/04/10)
We have identified and synthesized a series of 2,7-diamino-thiazolo[5,4-d]pyrimidines as TRPV1 antagonists. An exploration of the structure-activity relationships at the 2-, 5-, and 7-positions of the thiazolo[5,4-d]pyrimidine led to the identification of
Single-step syntheses of 2-amino-7-chlorothiazolo[5,4-d]pyrimidines: Intermediates for bivalent thiazolopyrimidines
Liu, Jian,Patch, Raymond J.,Schubert, Carsten,Player, Mark R.
, p. 10194 - 10197 (2007/10/03)
A single-step process for the preparation of 2-amino-7-chlorothiazolo[5,4- d]pyrimidines, 2, was achieved by the reaction of the commercially available 4,6-dichloro-5-aminopyrimidine 1 with isothiocyanates. This mild reaction accommodates a variety of fun
