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4-METHYL-2-MORPHOLIN-4-YL-PYRIMIDINE-5-CARBOXYLIC ACID is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 873450-22-7 Structure
  • Basic information

    1. Product Name: 4-METHYL-2-MORPHOLIN-4-YL-PYRIMIDINE-5-CARBOXYLIC ACID
    2. Synonyms: 4-METHYL-2-(4-MORPHOLINYL)-5-PYRIMIDINECARBOXYLIC ACID;4-METHYL-2-MORPHOLIN-4-YL-PYRIMIDINE-5-CARBOXYLIC ACID;5-PYRIMIDINECARBOXYLIC ACID, 4-METHYL-2-(4-MORPHOLINYL)-;AKOS VGYB0001116;OTAVA-BB 1086791;4-methyl-2-morpholinopyrimidine-5-carboxylic acid
    3. CAS NO:873450-22-7
    4. Molecular Formula: C10H13N3O3
    5. Molecular Weight: 223.23
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 873450-22-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-METHYL-2-MORPHOLIN-4-YL-PYRIMIDINE-5-CARBOXYLIC ACID(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-METHYL-2-MORPHOLIN-4-YL-PYRIMIDINE-5-CARBOXYLIC ACID(873450-22-7)
    11. EPA Substance Registry System: 4-METHYL-2-MORPHOLIN-4-YL-PYRIMIDINE-5-CARBOXYLIC ACID(873450-22-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 873450-22-7(Hazardous Substances Data)

873450-22-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 873450-22-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,3,4,5 and 0 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 873450-22:
(8*8)+(7*7)+(6*3)+(5*4)+(4*5)+(3*0)+(2*2)+(1*2)=177
177 % 10 = 7
So 873450-22-7 is a valid CAS Registry Number.

873450-22-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-methyl-2-morpholin-4-ylpyrimidine-5-carboxylic acid

1.2 Other means of identification

Product number -
Other names 5-Pyrimidinecarboxylic acid,4-methyl-2-(4-morpholinyl)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:873450-22-7 SDS

873450-22-7Downstream Products

873450-22-7Relevant articles and documents

IMIDAZO[4,5-C]PYRIDINE AND PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS SSAO INHIBITORS

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Page/Page column 37-38, (2014/09/29)

The compounds of formula (I) are inhibitors of semicarbazide- sensitive amine oxidase (SSAO) activity useful in the treatment of inflammation, an inflammatory disease, an immune or an autoimmune disorder, or inhibition of tumour growth.

Optimisation of pharmacokinetic properties in a neutral series of 11β-HSD1 inhibitors

Scott, James S.,Gill, Adrian L.,Godfrey, Linda,Groombridge, Sam D.,Rees, Amanda,Revill, John,Schofield, Paul,S?rme, Pernilla,Stocker, Andrew,Swales, John G.,Whittamore, Paul R.O.

, p. 6756 - 6761 (2013/01/14)

11β-HSD1 is increasingly seen as an attractive target for the treatment of type II diabetes and other elements of the metabolic syndrome. In this program of work we describe how a series of neutral 2-thioalkyl-pyridine 11β-HSD1 inhibitors were optimized in terms of their pharmacokinetic properties to give compounds with excellent bioavailability in both rat and dog through a core change to pyrimidine. A potential reactive metabolite issue with 4-thioalkyl-pyrimidines was circumvented by a switch from sulfur to carbon substitution.

SUBSTITUTED PYRIMIDIN-5-CARBOXAMIDES 281

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Page/Page column 38, (2009/10/30)

A compound of formula (I): and pharmaceutically-acceptable salts thereof wherein the variable groups are defined within; their use in the inhibition of 11betaHSD1, processes for making them and pharmaceutical compositions comprising them are also described.

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