- LXR AND FXR MODULATORS
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Compounds of the invention are disclosed, such as compounds of formulae LX - LXIV, and pharmaceutically acceptable salts, isomers, or prodrugs thereof, which are useful as modulators of the activity of liver X receptors (LXR) and Farnesoid X receptors (FXR), where R00, R200, R400, R500, J11, J21, G1, G21, and Q are defined herein. Pharmaceutical compositions containing the compounds and methods of using the compounds are also disclosed.
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Page/Page column 151
(2011/03/17)
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- Synthesis and Biological Evaluation of 6-Substituted 3-Aryl-2-methyl-4(3H)-pyrimidones
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6-Substituted 3-aryl-2-methyl-4(3H)-pyrimidones (III) have been prepared by the reaction of N-arylacetamidines (II) with various diplorophiles like ethyl propiolate, ethyl tetrolate and ethyl phenylpropiolate.The structure of the products has been confirm
- Gupta, K. A.,Saxena, Anil K.,Jain, Padam C.,Srimal, R. C.,Kar, K.,Anand, Nitya
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p. 384 - 387
(2007/10/02)
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