Synthesis of the N-acetylcysteamine thioester of seco-proansamitocin
(Chemical Equation Presented) The enantioselective total synthesis of the N-acetylcysteamine thioester of seco-proansamitocin, a key biosynthetic intermediate of the highly potent antitumor agent ansamitocin, is described, which twice utilizes the Nagao a
Frenzel, Thomas,Bruenjes, Marco,Quitschalle, Monika,Kirschning, Andreas
p. 135 - 138
(2007/10/03)
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