877041-47-9 Usage
Uses
Used in Pharmaceutical Research:
6-(TERT-BUTYL) 3-METHYL 2-AMINO-4,7-DIHYDROTHIENO[2,3-C]PYRIDINE-3,6(5H)-DICARBOXYLATE is used as a research compound for the development of new pharmaceutical agents. Its unique structure and functional groups make it a promising candidate for the design of novel drugs targeting specific biological pathways or receptors.
Used in Organic Synthesis:
In the field of organic synthesis, 6-(TERT-BUTYL) 3-METHYL 2-AMINO-4,7-DIHYDROTHIENO[2,3-C]PYRIDINE-3,6(5H)-DICARBOXYLATE serves as a key intermediate or building block in the synthesis of more complex organic molecules. Its versatile structure allows for further functionalization and modification, enabling the creation of a wide range of chemical entities with potential applications in various industries.
Used in Medicinal Chemistry:
6-(TERT-BUTYL) 3-METHYL 2-AMINO-4,7-DIHYDROTHIENO[2,3-C]PYRIDINE-3,6(5H)-DICARBOXYLATE is utilized as a scaffold in medicinal chemistry for the design and optimization of drug candidates. Its structural features, such as the thieno-pyridine core, carboxylate groups, and amino functionality, can be exploited to enhance the binding affinity, selectivity, and pharmacokinetic properties of potential therapeutic agents.
Used in Chemical Libraries:
6-(TERT-BUTYL) 3-METHYL 2-AMINO-4,7-DIHYDROTHIENO[2,3-C]PYRIDINE-3,6(5H)-DICARBOXYLATE is incorporated into chemical libraries for high-throughput screening in drug discovery. Its distinctive molecular architecture can contribute to the diversity of the library, increasing the chances of identifying lead compounds with novel mechanisms of action.
Used in Material Science:
In material science, 6-(TERT-BUTYL) 3-METHYL 2-AMINO-4,7-DIHYDROTHIENO[2,3-C]PYRIDINE-3,6(5H)-DICARBOXYLATE may be explored for its potential to form new materials with unique properties, such as conductivity, stability, or responsiveness to external stimuli. Its structural components could be tailored to create materials with specific applications in areas like sensors, catalysts, or advanced materials for energy storage or conversion.
Used in Agrochemical Development:
6-(TERT-BUTYL) 3-METHYL 2-AMINO-4,7-DIHYDROTHIENO[2,3-C]PYRIDINE-3,6(5H)-DICARBOXYLATE is employed as a starting material or intermediate in the development of new agrochemicals, such as pesticides or herbicides. Its chemical properties and reactivity may be harnessed to create compounds with improved efficacy, selectivity, and environmental compatibility.
Check Digit Verification of cas no
The CAS Registry Mumber 877041-47-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,7,0,4 and 1 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 877041-47:
(8*8)+(7*7)+(6*7)+(5*0)+(4*4)+(3*1)+(2*4)+(1*7)=189
189 % 10 = 9
So 877041-47-9 is a valid CAS Registry Number.
InChI:InChI=1/C14H20N2O4S/c1-14(2,3)20-13(18)16-6-5-8-9(7-16)21-11(15)10(8)12(17)19-4/h5-7,15H2,1-4H3
877041-47-9Relevant articles and documents
Preparation method and application of selective butyryl cholinesterase inhibitor. (by machine translation)
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Paragraph 0048-0050, (2020/03/12)
The invention discloses a preparation method and application (I) of the selective butyryl cholinesterase inhibitor, with the general formula. to evaluate the selectivity of cholinesterase inhibition activity, to find that it has good in-vitro activity and
Development of thieno- and benzopyrimidinone inhibitors of the Hedgehog signaling pathway reveals PDE4-dependent and PDE4-independent mechanisms of action
Hempel, Jonathan E.,Cadar, Adrian G.,Hong, Charles C.
supporting information, p. 1947 - 1953 (2016/04/05)
From a high content in vivo screen for modulators of developmental patterning in embryonic zebrafish, we previously identified eggmanone (EGM1, 3) as a Hedgehog (Hh) signaling inhibitor functioning downstream of Smoothened. Phenotypic optimization studies for in vitro probe development utilizing a Gli transcription-linked stable luciferase reporter cell line identified EGM1 analogs with improved potency and aqueous solubility. Mechanistic profiling of optimized analogs indicated two distinct scaffold clusters: PDE4 inhibitors able to inhibit downstream of Sufu, and PDE4-independent Hh inhibitors functioning between Smo and Sufu. Each class represents valuable in vitro probes for elucidating the complex mechanisms of Hh regulation.
NOVEL COMPOUND HAVING ANGIOGENESIS INHIBITORY ACTIVITY, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME
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Paragraph 0047; 0048; 00453; 00454, (2014/07/23)
Disclosed are an anti-angiogenic compound, represented by Chemical Formula I, or a pharmaceutically acceptable salt thereof, a preparation method thereof, and a pharmaceutically acceptable composition including the same. Because the compound of Chemical Formular I potently suppresses the angiogenesis, the compound of Chemical Formula I is applicable to the prevention and treatment of diseases caused by aberrant activity of vascular endothelial growth factor, and available as an anti-angiogenic agent.
