Construction of 1-pyrroline skeletons by Lewis acid-mediated conjugate addition of vinyl azides
Lewis acid-mediated conjugate addition of vinyl azides to electron-deficient alkenes led to the efficient construction of 1-pyrroline skeletons. The reactions of vinyl azides with 3-alkylidene-2-oxoindolines afford 3′,4′-dihydrospiro[indoline-3,2′-pyrrol]-2-ones in a diastereoselective fashion, whereas those with dimethyl 2-alkylidenemalonates provide 4,5-dihydro-3H-pyrroles.
Zhu, Xu,Chiba, Shunsuke
supporting information
p. 2473 - 2476
(2016/02/18)
Δ1-pyrroline based boranyls: Synthesis, crystal structures and luminescent properties
Two new Δ1-pyrroline ligands and their corresponding boron complexes have been synthesized and characterized. Their luminescent properties were investigated, the boron complexes emitting brightly around 410 nm. The presence of the exocyclic dou
Cardona, Francisco,Rocha, Jo?o,Silva, Artur M.S.,Guieu, Samuel
p. 16 - 20
(2014/06/24)
A facile synthesis of isoindoline and Δ1-pyrrolines from chalcone and glycine by a cascade of process involving addition, in situ decarboxylation, and cyclization
In this Letter, we report a rapid one-step entry into isoindoline and Δ1-pyrrolines from chalcone. The key step in the synthesis is the addition of glycine to chalcone. In acidic medium the reaction presumably goes through aza-Michael addition,
One-pot synthesis of substituted Δ1-pyrrolines through the Michael addition of nitroalkanes to chalcones and subsequent reductive cyclization in aqueous media
A facile and efficient one-pot synthesis of substituted Δ1-pyrrolines in aqueous media has been developed. Upon treatment with aqueous sodium hydroxide in N,N-dimethylformamide, a range of chalcones underwent room temperature Michael addition r