87774-48-9Relevant articles and documents
Construction of 1-pyrroline skeletons by Lewis acid-mediated conjugate addition of vinyl azides
Zhu, Xu,Chiba, Shunsuke
supporting information, p. 2473 - 2476 (2016/02/18)
Lewis acid-mediated conjugate addition of vinyl azides to electron-deficient alkenes led to the efficient construction of 1-pyrroline skeletons. The reactions of vinyl azides with 3-alkylidene-2-oxoindolines afford 3′,4′-dihydrospiro[indoline-3,2′-pyrrol]-2-ones in a diastereoselective fashion, whereas those with dimethyl 2-alkylidenemalonates provide 4,5-dihydro-3H-pyrroles.
A facile synthesis of isoindoline and Δ1-pyrrolines from chalcone and glycine by a cascade of process involving addition, in situ decarboxylation, and cyclization
Elamparuthi, Elangovan,Sarathkumar, Subramaniayan,Girija, Swaminathan,Anbazhagan, Veerappan
supporting information, p. 3992 - 3995 (2014/07/08)
In this Letter, we report a rapid one-step entry into isoindoline and Δ1-pyrrolines from chalcone. The key step in the synthesis is the addition of glycine to chalcone. In acidic medium the reaction presumably goes through aza-Michael addition,
