- Synthesis, characterization and biological activity of some dithiourea derivatives
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Novel dithiourea derivatives have been designed as HIV-1 protease inhibitors using Autodock 4.2, synthesized and characterized by spectroscopic methods and microanalysis. 1-(3-Bromobenzoyl)-3-[2-({[(3-bromophenyl)formami-do]methanethioyl}amino)phenyl]thio
- Frost, Carminita,Hoppe, Heinrich,Hosten, Eric,Isaacs, Michelle,Khanye, Setshaba D.,Krause, Jason,Lobb, Kevin,Odame, Felix,Sayed, Yasien,Tshentu, Zenixole
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p. 764 - 777
(2020/10/02)
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- Synthesis, characterization and antibacterial activity of new 1,2- and 1,4-bis(n'-substituted thioureido)benzene derivatives
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Synthesis of two series of 1,2- and 1,4-bis(thioureido)benzene derivatives was accomplished by the treatment of corresponding alkanoyl/aroyl chlorides with potassium thiocyanate in dry acetone to afford the respective isothiocyanates as intermediates. The
- Saeed, Aamer,Abbas, Naeem,Ashraf, Zaman,Bolte, Michael
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p. 273 - 278
(2013/12/04)
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- TRICYCLIC INHIBITORS OF PRO-MATRIX METALLOPROTEINASE ACTIVATION
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This invention relates to tricycle I and its therapeutic and prophylactic uses, wherein the variables C1, C2, Z1, Z2, Q, J, R1, and R3 are defined in the specification. Disorders treated and/or prevented include rheumatoid arthritis.
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Page/Page column 37
(2012/06/01)
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- An efficient one-pot synthesis of bis-1-(aroyl)-3-(aryl)thiourea
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A three-component and one-pot reaction between 2,6-diaminopyridine or 1,2-diaminobenzene and ammonium thiocyanate with the subsequent addition of an aroyl chloride afforded the bis-1-(aroyl)-3-(aryl)thiourea in excellent yields. It was important to make the thiocyanate derivatives first and then to use those to prepare the thiourea derivatives.
- Mohebat, Razieh,Mohammadian, Gholam
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p. 626 - 628
(2013/02/23)
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- Phase transfer catalyzed synthesis of arene-bis-aroyl thiourea derivatives
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Reaction of arene diamines with aroyl chloride and ammonium thiocyanate under the condition of solid-liquid phase transfer catalysis using polyethylene-glycol-600 (PEG-600) as the catalyst furnishes arene-bis-aroyl thioureas 3a-I in good to excellent yiel
- Zhang,Wei,Gao
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p. 700 - 702
(2007/10/03)
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- REACTIONS OF CARBONYL ISOTHIOCYANATES WITH NUCLEOPHILIC BIFUNCTIONAL REAGENTS
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Reactions of benzoyl-, 2-furoyl-, acetyl-, and trichloroacetyl isothiocyanates with 1,2-diaminobenzene, 2-aminophenol, 5,6-diamino-1,3-uracil and 2,3-diaminopyridine were investigated.Formation of the individual products and their IR, UV and electron impa
- Uher, Michal,Berkes, Dusan,Lesko, Jan,Floch, Lubomir
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p. 1651 - 1658
(2007/10/02)
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