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3-cyclopropylpyridin-2-amine is a chemical compound with the molecular formula C7H9N. It is an organic compound characterized by a cyclopropyl group attached to a pyridine ring, featuring an amine functional group at the 2-position. This unique structure and reactivity make it a valuable component in the synthesis of pharmaceuticals and other organic compounds. Its biological activity also positions it as a potential candidate for drug development, with potential applications in the treatment of certain diseases and medical conditions.

878805-25-5

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878805-25-5 Usage

Uses

Used in Pharmaceutical Synthesis:
3-cyclopropylpyridin-2-amine is used as a key intermediate in the synthesis of various pharmaceuticals due to its unique structure and reactivity. Its presence in the molecular framework can contribute to the development of new drugs with specific therapeutic properties.
Used in Drug Development:
3-cyclopropylpyridin-2-amine is used as a potential candidate for drug development because of its demonstrated biological activity. Its ability to interact with biological targets makes it a promising starting point for the creation of new therapeutic agents.
Used in the Treatment of Certain Diseases and Medical Conditions:
3-cyclopropylpyridin-2-amine has been studied for its potential use in treating specific diseases and medical conditions. Its application in this context is based on its capacity to modulate biological processes that are implicated in the pathophysiology of these conditions.
Used in Organic Chemistry Research:
3-cyclopropylpyridin-2-amine is utilized in organic chemistry research to explore new synthetic pathways and to understand the reactivity of cyclopropyl-pyridine systems. This can lead to the discovery of novel organic compounds with potential applications in various fields.

Check Digit Verification of cas no

The CAS Registry Mumber 878805-25-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,8,8,0 and 5 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 878805-25:
(8*8)+(7*7)+(6*8)+(5*8)+(4*0)+(3*5)+(2*2)+(1*5)=225
225 % 10 = 5
So 878805-25-5 is a valid CAS Registry Number.

878805-25-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-cyclopropylpyridin-2-amine

1.2 Other means of identification

Product number -
Other names 2-PYRIDINAMINE,3-CYCLOPROPYL

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:878805-25-5 SDS

878805-25-5Relevant articles and documents

HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES

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Paragraph 00217, (2020/11/03)

Provided herein are Heterocyclic compounds of formula (I): and pharmaceutically acceptable salts, tautomers, isotopologues, or stereoisomers thereof, wherein W, X, Y, R1, R2, and RN are as defined herein, compositions comprising an effective amount of a Heterocyclic Compound, and methods for treating or preventing animal and human filarial worm infections and diseases.

KRAS G12C INHIBITORS AND METHODS OF USING THE SAME

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Paragraph 0627, (2019/11/19)

Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.

Synthesis of bromocyclopropylpyridines via the Sandmeyer reaction

Striela, Romualdas,Urbelis, Gintaras,Sūd?ius, Jurgis,Ston?ius, Sigitas,Sadzevi?ien?, Rita,Labanauskas, Linas

supporting information, p. 1681 - 1683 (2017/04/06)

The reactions of 2-amino-5-cyclopropylpyridine with organic nitrites in the presence of copper(II) halides in various organic solvents were investigated. Optimal reaction conditions for the Sandmeyer reaction were developed and successfully applied to the synthesis of useful building blocks, bromo and chlorocyclopropylpyridines. Aminocyclopropylpyridines were synthesized in high yields from the corresponding aminobromopyridines under standard Suzuki coupling conditions.

TRICYCLIC DLK INHIBITORS AND USES THEREOF

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Page/Page column 76, (2016/09/26)

The invention relates to compounds of formula (I) and salts thereof, wherein ring A and R1-R2 have any of the values defined in the specification. The compounds and salts are useful for treating DLK mediated disorders. The invention also provides pharmaceutical compositions comprising a compound of formula (I), or a pharmaceutically acceptable salt thereof, as well as methods of using said compounds, salts, or compositions as DLK inhibitors and for treating neurodegeneration diseases and disorders.

3-SUBSTITUTED PYRAZOLES AND USE AS DLK INHIBITORS

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Page/Page column 109; 110, (2014/08/06)

The present invention provides for compounds of Formula (I) and various embodiments thereof, and compositions comprising compounds of Formula (I) and various embodiments thereof. (I) In compounds of Formula I, the groups R1, R2, R3, R4, R5, R6 and R7 have the meaning as described herein. The present invention also provides for methods of using compounds of Formula I and compositions comprising compounds of Formula (I) as DLK inhibitors and for treating neurodegeneration diseases and disorders.

HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF

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Paragraph 00340, (2014/01/09)

Provided herein are heteroaryl compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. In one embodiment, the compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as CNS disorders and metabolic disorders, including, but not limited to, e.g., neurological disorders, psychosis, schizophrenia, obesity, and diabetes.

NOVEL SUBSTITUTED IMIDAZOLE DERIVATIVES

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Page/Page column 83, (2010/11/27)

The present invention relates to a compound represented by Formula [I] or a pharmaceutically acceptable salt or ester thereof: wherein: X1, X2, X3, and X4, which may be identical or different, are each C or N, provided that none to two of X1, X2, X3, and X4 is/are N; Y is CH or N; R1, R1', R2, R2', R3, R3', R4, and R4', which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the like; R5 is a hydrogen atom or a methyl group; R6 and R7, which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the like; R8 and R8', which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the like; R9 is an aryl group or a heteroaryl group which may be substituted; and n is an integer from 1 to 3, and a PLK1 inhibitor or an anticancer agent containing the same.

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