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[6R-[6alpha,7beta(R)]]-3-(acetoxymethyl)-7-[(formyloxy)phenylacetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is a complex penicillin derivative featuring a bicyclic ring system with a thiazolidine and a beta-lactam ring. This potent antibiotic inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, making it effective against a range of bacterial infections. The presence of acetoxymethyl and formyloxy groups enhances its solubility and stability, allowing for various formulations suitable for oral and intravenous administration.

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  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 3-[(acetyloxy)methyl]-7-[[(formyloxy)phenylacetyl]amino]-8-oxo-, [6R-[6a,7b(R*)]]- (9CI)

    Cas No: 87932-78-3

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  • [6R-[6alpha,7beta(R*)]]-3-(acetoxymethyl)-7-[(formyloxy)phenylacetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

    Cas No: 87932-78-3

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  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 3-[(acetyloxy)methyl]-7-[[(formyloxy)phenylacetyl]amino]-8-oxo-, [6R-[6a,7b(R*)]]- (9CI)

    Cas No: 87932-78-3

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  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 3-[(acetyloxy)methyl]-7-[[(formyloxy)phenylacetyl]amino]-8-oxo-, [6R-[6a,7b(R*)]]- (9CI)

    Cas No: 87932-78-3

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  • 87932-78-3 Structure
  • Basic information

    1. Product Name: [6R-[6alpha,7beta(R*)]]-3-(acetoxymethyl)-7-[(formyloxy)phenylacetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
    2. Synonyms: [6R-[6alpha,7beta(R*)]]-3-(acetoxymethyl)-7-[(formyloxy)phenylacetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;3-ACETOXYMETHYL-7-[(R)-2-FORMYLOXY-2-PHENYLACETAMIDO]-3-CEPHEM-4-CARBOXYLIC ACID;(7R)-3-[(Acetyloxy)methyl]-7-[[(R)-(formyloxy)phenylacetyl]amino]cepham-3-ene-4-carboxylic acid;(6R-(6alpha,7beta(R*)))-3-(Acetoxymethyl)-7-((formyloxy)phenylacetamido)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid;Einecs 289-358-9;Cefamandole Impurity E
    3. CAS NO:87932-78-3
    4. Molecular Formula: C19H18N2O8S
    5. Molecular Weight: 434.41982
    6. EINECS: 289-358-9
    7. Product Categories: N/A
    8. Mol File: 87932-78-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: [6R-[6alpha,7beta(R*)]]-3-(acetoxymethyl)-7-[(formyloxy)phenylacetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid(CAS DataBase Reference)
    10. NIST Chemistry Reference: [6R-[6alpha,7beta(R*)]]-3-(acetoxymethyl)-7-[(formyloxy)phenylacetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid(87932-78-3)
    11. EPA Substance Registry System: [6R-[6alpha,7beta(R*)]]-3-(acetoxymethyl)-7-[(formyloxy)phenylacetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid(87932-78-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 87932-78-3(Hazardous Substances Data)

87932-78-3 Usage

Uses

Used in Pharmaceutical Industry:
[6R-[6alpha,7beta(R)]]-3-(acetoxymethyl)-7-[(formyloxy)phenylacetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is used as an antibiotic for the treatment of bacterial infections. Its ability to inhibit bacterial cell wall synthesis by binding to penicillin-binding proteins makes it a valuable asset in combating various bacterial pathogens. [6R-[6alpha,7beta(R)]]-3-(acetoxymethyl)-7-[(formyloxy)phenylacetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid's solubility and stability, attributed to its acetoxymethyl and formyloxy groups, facilitate its administration in different formulations, such as oral and intravenous, to cater to diverse patient needs.

Check Digit Verification of cas no

The CAS Registry Mumber 87932-78-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,9,3 and 2 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 87932-78:
(7*8)+(6*7)+(5*9)+(4*3)+(3*2)+(2*7)+(1*8)=183
183 % 10 = 3
So 87932-78-3 is a valid CAS Registry Number.

87932-78-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (6R,7R)-3-(acetyloxymethyl)-7-[[(2R)-2-formyloxy-2-phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

1.2 Other means of identification

Product number -
Other names EINECS 289-358-9

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:87932-78-3 SDS

87932-78-3Relevant articles and documents

Spirocyclic Side-chain Derivatives of Penicillin and Cephalosporin

Sammes, Peter G.,Smith, Steven,Ross, Barry C.

, p. 2117 - 2124 (2007/10/02)

A series of two spirocyclic oxazolidinone derivatives of penicillin and four derivatives of cephalosporin have been prepared, as well as a benzoxazine conjugate of cephalosporin, with the object of freezing the conformation of the 6(7)-amide side-chain bearing a pendant aromatic ring.The antibacterial properties of these derivatives are discussed.

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