879887-32-8

Basic information

• Product Name: 1-Boc-5-formylindoline
• Synonyms: 1-Boc-5-formylindoline;1H-Indole-1-carboxylicacid,5-forMyl-2,3-dihydro-,1,1-diMethylethylester;tert-butyl 5-formylindoline-1-carboxylate;5-Formyl-2,3-dihydro-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester
• CAS NO: 879887-32-8
• Molecular Formula: C₁₄H₁₇NO₃
• Molecular Weight: 247
• Mol File: 879887-32-8.mol

Chemical Properties

• Boiling Point: 382.1±41.0 °C(Predicted)
• Appearance: /
• Density: 1.186±0.06 g/cm3(Predicted)
• PKA: -2.49±0.20(Predicted)
• CAS DataBase Reference: 1-Boc-5-formylindoline(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Boc-5-formylindoline(879887-32-8)
• EPA Substance Registry System: 1-Boc-5-formylindoline(879887-32-8)

Safety Data

• Hazardous Substances Data: 879887-32-8(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
1-Boc-5-formylindoline is used as a key intermediate for the synthesis of heterocyclic compounds, which are essential in the development of new materials, pharmaceuticals, and agrochemicals. Its unique structure allows for versatile reactions and the formation of complex molecules.
Used in Pharmaceutical Research:
1-Boc-5-formylindoline is used as a building block in the design and synthesis of novel drug candidates. Its reactivity and structural features enable the creation of potential therapeutic agents with improved properties, such as enhanced efficacy, selectivity, and reduced side effects.
Used in Agrochemical Development:
1-Boc-5-formylindoline is used as a precursor in the synthesis of agrochemicals, such as pesticides and herbicides. Its potential to form heterocyclic compounds makes it a valuable component in the development of new and more effective crop protection products.
Used in Academic Research:
1-Boc-5-formylindoline is used as a model compound in the study of organic reactions and mechanisms. Its unique properties and reactivity provide insights into the fundamental principles of synthetic chemistry and contribute to the advancement of chemical knowledge.

Upstream product

• 350683-41-9 1-Boc-5-hydroxymethylindoline 
• 279256-09-6 1-(tert-butyloxycarbonyl)indole-5-carboxaldehyde 
• 24424-99-5 di-tert-butyl dicarbonate 
• 261732-38-1 tert-butyl 5-bromoindoline-1-carboxylate 
• 68-12-2 N,N-dimethyl-formamide 
• 1196-69-6 1H-indole-5-carboxaldehyde 

Downstream Products

• 1118649-53-8 5-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl]-2,3-dihydro-1H-indole 
• 1118651-99-2 5-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl]-N-ethyl-2,3-dihydro-1H-indol-1-carboxamide 
• 1187196-61-7 tert-butyl 5-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-isoxazol-3-yl]-2,3-dihydro-1H-indol-1-carboxylate 
• 957204-40-9 1-(tert-butoxycarbonyl)-5-[(E)-2-(4-phenyl-5-trifluormethyl-2-thienyl)ethenyl]indoline 

Relevant articles and documents

PESTICIDAL CONDENSED - RING ARYL COMPOUNDS

Condensed-ring aryl compounds of formula (I) and use of the same as a agrochemical for controlling noxious organisms wherein (X)mQ, A, R1, (Y)n and the grouping -W1-W2-W3-W4- are as defined herein.

HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE

To provide a novel compound which has S1P receptor agonistic activity, exhibits excellent immunosuppressing effect, gives less adverse side effects, and can be orally administered. The invention provides a compound represented by general formula (I) (wherein A is a single bond, -O-, or - CH2-; R1 represents a hydrogen atom or a C1-C6 alkyl group, and V represents any one group selected from among the following groups (1) to (3) : (1) -G1-, (2) -G2-N(R2) -G3-, and (3) a group represented by formula 2, wherein each of Z1 and Z2 represents a hydrogen atom or a C1-C6 alkyl group, Z3 represents a hydrogen or the like, Q represents -CH2-O- or the like, and Y represents a group represented by foumula 3, a salt thereof, or a solvate thereof.

Sulfonamide bicyclic compounds

The invention encompasses compounds of Formula I, including pharmaceutically acceptable salts and solvates, their pharmaceutical compositions, and their uses in inhibiting β-amyloid peptide (β-AP) production.