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4-CHLORO-3,5-DINITROBENZENESULFONIC ACID, also known as CDNSA, is a chemical compound characterized by its molecular formula C6H3ClN2O7S. It presents as a yellow to orange crystalline powder, widely recognized for its role as a reagent in the chemical industry. CDNSA is a potent sulfonating agent, which makes it valuable in the synthesis of dyes, pharmaceuticals, and various organic compounds. Its applications extend to analytical chemistry, where it serves as a reagent for the detection and determination of amino acids, proteins, and peptides. Despite its utility, CDNSA is acknowledged for its toxicity and potential to cause irritation to the skin, eyes, and respiratory system, necessitating careful handling.

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  • 88-91-5 Structure
  • Basic information

    1. Product Name: 4-CHLORO-3,5-DINITROBENZENESULFONIC ACID
    2. Synonyms: 4-CHLORO-3,5-DINITROBENZENESULFONIC ACID;4-chloro-3,5-dinitrobenzenesulphonic acid;3,5-Dinitro-4-chlorobenzenesulfonic acid;Benzenesulfonic acid,4-chloro-3,5-dinitro-
    3. CAS NO:88-91-5
    4. Molecular Formula: C6H3ClN2O7S
    5. Molecular Weight: 282.62
    6. EINECS: 201-868-5
    7. Product Categories: N/A
    8. Mol File: 88-91-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.911 g/cm3
    6. Refractive Index: 1.651
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-CHLORO-3,5-DINITROBENZENESULFONIC ACID(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-CHLORO-3,5-DINITROBENZENESULFONIC ACID(88-91-5)
    11. EPA Substance Registry System: 4-CHLORO-3,5-DINITROBENZENESULFONIC ACID(88-91-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 88-91-5(Hazardous Substances Data)

88-91-5 Usage

Uses

Used in Chemical Industry:
4-CHLORO-3,5-DINITROBENZENESULFONIC ACID is used as a strong sulfonating agent for the production of dyes, pharmaceuticals, and other organic compounds, due to its ability to facilitate the formation of sulfonic acid derivatives.
Used in Analytical Chemistry:
In the field of analytical chemistry, 4-CHLORO-3,5-DINITROBENZENESULFONIC ACID is used as a reagent for the determination of amino acids, proteins, and peptides, leveraging its capacity to interact with these biomolecules and aid in their identification and quantification.
Used in Disease and Disorder Research:
4-CHLORO-3,5-DINITROBENZENESULFONIC ACID is also being investigated for its potential use in the treatment of certain diseases and disorders, capitalizing on its chemical properties to explore its therapeutic effects and possible applications in medicine.

Check Digit Verification of cas no

The CAS Registry Mumber 88-91-5 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 8 and 8 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 88-91:
(4*8)+(3*8)+(2*9)+(1*1)=75
75 % 10 = 5
So 88-91-5 is a valid CAS Registry Number.
InChI:InChI=1/C6H3ClN2O7S/c7-6-4(8(10)11)1-3(17(14,15)16)2-5(6)9(12)13/h1-2H,(H,14,15,16)

88-91-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-CHLORO-3,5-DINITROBENZENESULFONIC ACID

1.2 Other means of identification

Product number -
Other names 4-chloro-3,5-dinitro-benzenesulfonic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:88-91-5 SDS

88-91-5Relevant articles and documents

Construction of phenoxazine rings containing nitro and sulfonic acid groups leading to phenoxazine-3-sulfonamide derivatives: Their evaluation as novel and potential insulin secretagogues

Reddy, Seelam Venkata,Rao, Gangula Mohan,Kumar, Baru Vijaya,Reddy, Koppela Naresh,Sravya, Konda,Goverdhan, Puchchakayala,Rathore, Vandana,Deora, Girdhar Singh,Pal, Manojit

, p. 587 - 592 (2014)

A series of N-(alkyl/aryl/heteroaryl)-1-nitro-10H-phenoxazine-3- sulfonamides was designed, synthesized and evaluated for its hypoglycemic, hyperglycemic and oral anti-diabetic activities. These compounds were prepared via the construction of a phenoxazine ring containing nitro and sulfonic acid groups in a single step followed by further transformations. One of these compounds exhibited promising anti-diabetic activities comparable to glibenclamide and increased serum insulin levels indicating its potential as a novel insulin secretagogue. This journal is the Partner Organisations 2014.

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