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880362-02-7

(S)-3-(2-METHOXYETHOXY)PYRROLIDINE is a chiral pyrrolidine derivative characterized by a pyrrolidine ring with a methoxyethoxy group attached to the third carbon atom. This unique structural feature results in two enantiomers, (S)and (R)-3-(2-methoxyethoxy)pyrrolidine. It is known for its versatile applications in the synthesis of pharmaceuticals, agrochemicals, and as an additive in material science and industrial products.

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  • 880362-02-7 Structure

  • Basic information

    1. Product Name: (S)-3-(2-METHOXYETHOXY)PYRROLIDINE
    2. Synonyms: (3S)-3-(2-Methoxyethoxy)pyrrolidine;(S)-3-(2-METHOXYETHOXY)PYRROLIDINE HCL;(S)-3-(2-METHOXYETHOXY)PYRROLIDINE HOAC;(S)-3-(2-METHOXYETHOXY)PYRROLIDINE
    3. CAS NO:880362-02-7
    4. Molecular Formula: C7H15NO2
    5. Molecular Weight: 145.2
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 880362-02-7.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 197.6°C at 760 mmHg
    3. Flash Point: 73.5°C
    4. Appearance: /
    5. Density: 0.98g/cm3
    6. Vapor Pressure: 0.376mmHg at 25°C
    7. Refractive Index: 1.45
    8. Storage Temp.: 2-8°C
    9. Solubility: N/A
    10. CAS DataBase Reference: (S)-3-(2-METHOXYETHOXY)PYRROLIDINE(CAS DataBase Reference)
    11. NIST Chemistry Reference: (S)-3-(2-METHOXYETHOXY)PYRROLIDINE(880362-02-7)
    12. EPA Substance Registry System: (S)-3-(2-METHOXYETHOXY)PYRROLIDINE(880362-02-7)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 880362-02-7(Hazardous Substances Data)

880362-02-7 Usage

Uses

Used in Pharmaceutical and Agrochemical Synthesis:
(S)-3-(2-METHOXYETHOXY)PYRROLIDINE is used as a building block for the synthesis of various pharmaceuticals and agrochemicals due to its unique structural and chemical properties. Its chiral nature allows for the creation of enantiomer-specific compounds, which can have different biological activities and selectivity.
Used in Organic Synthesis:
(S)-3-(2-METHOXYETHOXY)PYRROLIDINE is utilized as a key intermediate in organic synthesis, enabling the development of novel compounds with potential applications in various fields, such as medicine, agriculture, and material science.
Used in Material Science:
(S)-3-(2-METHOXYETHOXY)PYRROLIDINE is employed as a modifier in material science to alter the physical and chemical properties of materials. Its ability to modify properties makes it a valuable component in the development of new materials with improved characteristics.
Used in Polymer Manufacturing:
(S)-3-(2-METHOXYETHOXY)PYRROLIDINE is used as an additive in the manufacturing of polymers and other industrial products. Its incorporation can enhance the properties of polymers, such as solubility, stability, and reactivity, making them suitable for a wide range of applications.

Check Digit Verification of cas no

The CAS Registry Mumber 880362-02-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,0,3,6 and 2 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 880362-02:
(8*8)+(7*8)+(6*0)+(5*3)+(4*6)+(3*2)+(2*0)+(1*2)=167
167 % 10 = 7
So 880362-02-7 is a valid CAS Registry Number.
InChI:InChI=1/C7H15NO2/c1-9-4-5-10-7-2-3-8-6-7/h7-8H,2-6H2,1H3/t7-/m0/s1

880362-02-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name (3S)-3-(2-methoxyethoxy)pyrrolidine

1.2 Other means of identification

Product number -
Other names (S)-3-(2-Methoxyethoxy)pyrrolidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:880362-02-7 SDS

880362-02-7Downstream Products

880362-02-7Relevant articles and documents

4-PYRIDONE COMPOUND OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION AND FORMULATION INCLUDING SAME

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Paragraph 0528; 0532-0536; 0537-0539, (2020/02/08)

An object of the present invention is to provide a compound or a salt thereof having anti-HBV activity, a pharmaceutical composition, an anti-hepatitis B virus agent, a production inhibitor of DNA of a hepatitis B virus, and a production or secretion inhibitor of a hepatitis B surface antigen. According to the present invention, provided are a compound represented by General Formula [1] or a salt thereof: (in the formula, R1 represents a benzothiazolyl group which may be substituted (in which a carbon atom constituting the 6-membered ring of the benzothiazolyl group of R1 is bonded to the nitrogen atom of the pyridone ring); R2 represents a C2-6 alkenyl group which may be substituted, or the like; and R3 represents a hydrogen atom or the like).

Discovery of highly potent and selective pan-Aurora kinase inhibitors with enhanced in vivo antitumor therapeutic index

Liu, Gang,Abraham, Sunny,Tran, Lan,Vickers, Troy D.,Xu, Shimin,Hadd, Michael J.,Quiambao, Sheena,Holladay, Mark W.,Hua, Helen,Ford Pulido, Julia M.,Gunawardane, Ruwanthi N.,Davis, Mindy I.,Eichelberger, Shawn R.,Apuy, Julius L.,Gitnick, Dana,Gardner, Michael F.,James, Joyce,Breider, Mike A.,Belli, Barbara,Armstrong, Robert C.,Treiber, Daniel K.

scheme or table, p. 3250 - 3260 (2012/06/01)

Serine/threonine protein kinases Aurora A, B, and C play essential roles in cell mitosis and cytokinesis. Currently a number of Aurora kinase inhibitors with different isoform selectivities are being evaluated in the clinic. Herein we report the discovery and characterization of 21c (AC014) and 21i (AC081), two structurally novel, potent, kinome-selective pan-Aurora inhibitors. In the human colon cancer cell line HCT-116, both compounds potently inhibit histone H3 phosphorylation and cell proliferation while inducing 8N polyploidy. Both compounds administered intravenously on intermittent schedules displayed potent and durable antitumor activity in a nude rat HCT-116 tumor xenograft model and exhibited good in vivo tolerability. Taken together, these data support further development of both 21c and 21i as potential therapeutic agents for the treatment of solid tumors and hematological malignancies.

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