A new synthetic approach to pyrrolo[3,4-a]indolizines
2-Pyridineacetonitrile was found to react with 1,3-dichloro-2-propanone in the presence of chlorotrimethylsilane yielding 2-chloromethyl-1- indolizinecarbonitrile. The chlorine atom in the prepared indolizine was replaced by various nucleophiles including
Tereshchenko, Alexander D.,Sysoiev, Dmitry A.,Tverdokhlebov, Anton V.,Tolmachev, Andrey A.
p. 349 - 353
(2007/10/03)
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