881189-58-8 Usage
Uses
Used in Pharmaceutical Research and Drug Development:
3-(5-Bromo-2-fluorophenyl)propionic acid is used as a building block for the synthesis of more complex molecules. Its unique structure allows for the creation of new compounds with potential therapeutic properties.
3-(5-Bromo-2-fluorophenyl)propionic acid is also used as a precursor in the development of new pharmaceuticals. Its presence in a molecule can contribute to desired biological activities, making it a valuable component in the design of novel drugs.
Used in Chemical Synthesis:
3-(5-Bromo-2-fluorophenyl)propionic acid is used as a starting material in the synthesis of various organic compounds. Its reactive functional groups can be modified to produce a wide range of chemical products for different applications.
Used in Medicinal Chemistry:
3-(5-Bromo-2-fluorophenyl)propionic acid is used as a key intermediate in the design and synthesis of new drugs. Its structural features can be exploited to create molecules with improved pharmacological properties, such as increased potency, selectivity, and reduced side effects.
The specific properties and potential uses of 3-(5-Bromo-2-fluorophenyl)propionic acid will depend on the research and development efforts of scientists and pharmaceutical companies. Its versatility and unique structural features make it a promising candidate for various applications in the chemical and pharmaceutical industries.
Check Digit Verification of cas no
The CAS Registry Mumber 881189-58-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,1,1,8 and 9 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 881189-58:
(8*8)+(7*8)+(6*1)+(5*1)+(4*8)+(3*9)+(2*5)+(1*8)=208
208 % 10 = 8
So 881189-58-8 is a valid CAS Registry Number.
881189-58-8Relevant articles and documents
Design and synthesis of novel meta-linked phenylglycine macrocyclic FVIIa inhibitors
Richter, Jeremy M.,Cheney, Daniel L.,Bates, J. Alex,Wei, Anzhi,Luettgen, Joseph M.,Rendina, Alan R.,Harper, Timothy M.,Narayanan, Rangaraj,Wong, Pancras C.,Seiffert, Dietmar,Wexler, Ruth R.,Priestley, E. Scott
, p. 67 - 72 (2017/12/12)
Two novel series of meta-linked phenylglycine-based macrocyclic FVIIa inhibitors have been designed to improve the rodent metabolic stability and PK observed with the precursor para-linked phenylglycine macrocycles. Through iterative structure-based design and optimization, the TF/ FVIIa Ki was improved to subnanomolar levels with good clotting activity, metabolic stability, and permeability.
MACROCYCLIC FACTOR VIIA INHIBITORS
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, (2015/01/09)
The present invention provides compounds of Formula (I) as defined in the specification and compositions comprising any of such novel compounds. These compounds are Factor VIIa inhibitors which may be used as medicaments.
CYCLIC AMINE DERIVATIVE OR SALT THEREOF
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Page/Page column 22; 43, (2010/11/27)
Provided are compounds which are an NMDA antagonist having a broad safety margin and are useful as a treating agent or a preventing agent for Alzheimer's disease, cerebrovascular dementia, Parkinson's disease, ischemic apoplexy, pain, etc. Concretely prov
