An improved method for the bromination of metalated haloarenes via lithium, zinc transmetalation: A convenient synthesis of 1,2-dibromoarenes
A facile protocol for the synthesis of 1,2-dibromoarenes is described. A standard ortho-lithiation/bromination procedure, when applied to bromoarenes, resulted in poor yields of the corresponding 1,2-dibromoarenes (13-62% yield). However, transmetalation
Menzel, Karsten,Fisher, Ethan L.,DiMichele, Lisa,Frantz, Doug E.,Nelson, Todd D.,Kress, Michael H.