884495-48-1 Usage
Uses
Used in Organic Synthesis:
3-Fluoro-2-formyl-6-methylpyridine is used as a building block in organic synthesis for the creation of various biologically active compounds. Its unique structure allows for the formation of diverse chemical entities with potential applications in different fields.
Used in Pharmaceutical Research:
In pharmaceutical research, 3-Fluoro-2-formyl-6-methylpyridine is utilized as a reagent in the preparation of heterocyclic compounds. These heterocyclic compounds are essential components in the development of new drugs, offering novel therapeutic options for various diseases and conditions.
Used in Agrochemical Development:
3-Fluoro-2-formyl-6-methylpyridine also has potential applications in the field of agrochemicals. It can be used as a precursor for the synthesis of complex organic molecules that can be employed as pesticides, herbicides, or other agricultural chemicals to improve crop yield and protect plants from pests.
Used in Material Science:
Furthermore, 3-Fluoro-2-formyl-6-methylpyridine has potential applications in material science. Its unique properties can be harnessed to develop new materials with specific characteristics, such as improved stability, reactivity, or selectivity, which can be useful in various industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 884495-48-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,4,4,9 and 5 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 884495-48:
(8*8)+(7*8)+(6*4)+(5*4)+(4*9)+(3*5)+(2*4)+(1*8)=231
231 % 10 = 1
So 884495-48-1 is a valid CAS Registry Number.
884495-48-1Relevant articles and documents
BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS
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Page/Page column 427-428, (2017/12/18)
This invention is directed to benzenesulfonamide compounds, as stereoisomers, enantiomers, tautomers thereof or mixtures thereof; or pharmaceutically acceptable salts, solvates or prodrugs thereof, for the treatment of diseases or conditions associated with voltage-gated sodium channels, such as epilepsy.
Synthesis and biological evaluation of 5-(fluoro-substituted-6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)imidazoles as inhibitors of transforming growth factor-β type i receptor kinase
Krishnaiah, Maddeboina,Jin, Cheng Hua,Sheen, Yhun Yhong,Kim, Dae-Kee
supporting information, p. 5228 - 5231 (2015/11/09)
To further optimize a clinical candidate 5 (EW-7197), a series of 5-(3-, 4-, or 5-fluoro-substituted-6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)imidazoles 19a-l have been synthesized and evaluated for their TGF-β type I receptor kinase (ALK5) and p38α MAP kinase inhibitory activity in an enzyme assay. The 5-(5-fluoro-substituted-6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)imidazoles 19h-l displayed the similar level of potency to that of 5 against both ALK5 (IC50 = 7.68-13.70 nM) and p38α MAP kinase (IC50 = 1240-3370 nM). Among them, 19j inhibited ALK5 with IC50 value of 7.68 nM in a kinase assay and displayed 82% inhibition at 100 nM in a luciferase reporter assay.