884874-01-5

Basic information

• Product Name: 2H-Indazole, 2-[(3-fluorophenyl)methyl]-5-nitro-
• Synonyms: 2H-Indazole, 2-[(3-fluorophenyl)methyl]-5-nitro-
• CAS NO: 884874-01-5
• Molecular Formula: C₁₄H₁₀FN₃O₂
• Molecular Weight: 271.2465032
• Mol File: 884874-01-5.mol

Chemical Properties

• Boiling Point: 472.2±30.0 °C(Predicted)
• Appearance: /
• Density: 1.38±0.1 g/cm3(Predicted)
• PKA: -1.41±0.30(Predicted)
• CAS DataBase Reference: 2H-Indazole, 2-[(3-fluorophenyl)methyl]-5-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Indazole, 2-[(3-fluorophenyl)methyl]-5-nitro-(884874-01-5)
• EPA Substance Registry System: 2H-Indazole, 2-[(3-fluorophenyl)methyl]-5-nitro-(884874-01-5)

Safety Data

• Hazardous Substances Data: 884874-01-5(Hazardous Substances Data)

Upstream product

• 65750-01-8 5-nitro-2H-indazole 
• 456-41-7 1-(Bromomethyl)-3-fluorobenzene 
• 5401-94-5 5-nitroindazole 

Downstream Products

• 202197-31-7 1-(3-fluorobenzyl)-1H-indazol-5-ylamine 

Relevant articles and documents

Hetero-aromatic compound and its use in medicine

The invention provides a hetero-aromatic compound or a stereisomer, geometric isomer, tautomer, despinner, nitrogen oxide, hydrate, solvate, metabolite, metabolism precursor and pharmaceutically acceptable salt or prodrug thereof, which is used for treating proliferative diseases. The invention also discloses a pharmaceutical composition containing the compound and an application of the compound or pharmaceutical composition thereof in preparation of a medicine for treating proliferative diseases.

Cyanoguanidines and cyanoamidines as ErbB2 and EGFR inhibitors

Cyanoguanidine quinazoline and cyanoamidine quinazolamine derivatives that are useful in the treatment of hyperproliferative diseases are disclosed. Methods of treating hyperproliferative diseases in mammals are also disclosed.