885270-70-2

Basic information

• Product Name: (3-AMINO-4-BROMO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER
• Synonyms: (3-AMINO-4-BROMO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER;2-Amino-4-Boc-amino-phenylbromide;tert-Butyl (3-aMino-4-broMophenyl)carbaMate;Carbamic acid, (3-amino-4-bromophenyl)-, 1,1-dimethylethyl ester (9CI)
• CAS NO: 885270-70-2
• Molecular Formula: C11H15BrN2O2
• Molecular Weight: 287.15
• Mol File: 885270-70-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3-AMINO-4-BROMO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (3-AMINO-4-BROMO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER(885270-70-2)
• EPA Substance Registry System: (3-AMINO-4-BROMO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER(885270-70-2)

Safety Data

• Hazardous Substances Data: 885270-70-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(3-AMINO-4-BROMO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and reactivity make it a valuable component in the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical industry, (3-AMINO-4-BROMO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER serves as an intermediate in the production of agrochemicals. Its properties contribute to the creation of effective pesticides, herbicides, and other agricultural chemicals.
Used in Research and Development:
(3-AMINO-4-BROMO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER is utilized in research and development for the exploration of new compounds and materials. Its versatile reactivity allows scientists to investigate its potential applications in various fields, leading to advancements in chemical synthesis and material science.
It is crucial to handle (3-AMINO-4-BROMO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER with care due to its potential hazardous properties. Proper safety protocols and guidelines should be followed during its use to ensure the safety of individuals and the environment.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 53324-38-2 4-bromo-3-nitroaniline 
• 1380445-22-6 (4-bromo-3-nitrophenyl)carbamic acid tert-butyl ester 

Relevant articles and documents

MACROCYCLIC SPIROCARBAMATE DERIVATIVES AS FACTOR XIA INHIBITORS, PHARMACEUTICALLY ACCEPTABLE COMPOSITIONS AND THEIR USE

The present invention provides a compound of Formula (I) and stereoisomers thereof, and pharmaceutically acceptable salts of said compounds and said stereoisomers, and pharmaceutical compositions thereof, and methods for using said compounds and compositi

FACTOR XIa INHIBITORS

The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIa inhibitors or dual inhibitors of Factor XIa and plasma Kallikrein.

Rh2(II)-catalyzed ester migration to afford 3 H-indoles from trisubstituted styryl azides

Rh2(II)-Complexes trigger the formation of 3H-indoles from ortho-alkenyl substituted aryl azides. This reaction occurs through a 4π-electron-5-atom electrocyclization of the rhodium N-aryl nitrene followed by a [1,2]-migration to afford only 3H-indoles. The selectivity of the migration is dependent on the identity of the β-styryl substituent.