885949-72-4

Basic information

• Product Name: (4-AMINOPHENYL)[4-(2-PYRIMIDINYL)PIPERAZINO]METHANONE
• Synonyms: (4-AMINOPHENYL)[4-(2-PYRIMIDINYL)PIPERAZINO]METHANONE;(4-Aminophenyl)[4-(pyrimidin-2-yl)piperazino]methanone;1-(4-Aminobenzoyl)-4-(pyrimidin-2-yl)piperazine;(4-Aminophenyl)[4-(pyrimidin-2-yl)piperazin-1-yl]methanone;1-(4-Aminobenzoyl)-4-(pyrimidin-2-yl)piperazine, 4-{[4-(Pyrimidin-2-yl)piperazin-1-yl]carbonyl}aniline, 2-[4-(4-Aminobenzoyl)piperazin-1-yl]pyrimidine
• CAS NO: 885949-72-4
• Molecular Formula: C₁₅H₁₇N₅O
• Molecular Weight: 283.33
• Mol File: 885949-72-4.mol

Chemical Properties

• Melting Point: 216
• Boiling Point: 562.9±60.0 °C(Predicted)
• Appearance: /
• Density: 1.296±0.06 g/cm3(Predicted)
• PKA: 4.87±0.33(Predicted)
• CAS DataBase Reference: (4-AMINOPHENYL)[4-(2-PYRIMIDINYL)PIPERAZINO]METHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: (4-AMINOPHENYL)[4-(2-PYRIMIDINYL)PIPERAZINO]METHANONE(885949-72-4)
• EPA Substance Registry System: (4-AMINOPHENYL)[4-(2-PYRIMIDINYL)PIPERAZINO]METHANONE(885949-72-4)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 885949-72-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research and Development:
(4-AMINOPHENYL)[4-(2-PYRIMIDINYL)PIPERAZINO]METHANONE is used as a chemical compound in pharmaceutical research and development for the discovery of new drugs. Its unique structure and potential pharmacological activities make it a promising candidate for further study and development in the medical field.
Used in Treatment of Various Medical Conditions:
(4-AMINOPHENYL)[4-(2-PYRIMIDINYL)PIPERAZINO]METHANONE is being studied for its potential use in the treatment of various medical conditions. Its exact mechanisms of action and therapeutic applications are still under investigation, but the compound's unique properties suggest it may have significant potential in this area.

Upstream product

• 20980-22-7 N-(2-pyridinyl)piperazine 
• 150-13-0 4-amino-benzoic acid 
• 122-04-3 4-nitro-benzoyl chloride 

Downstream Products

• 1622306-20-0 C₂₂H₂₃N₅O 

Relevant articles and documents

ANTI-PCSK9 COMPOUNDS AND METHODS FOR THE TREATMENT AND/OR PREVENTION OF CARDIOVASCULAR DISEASES

Disclosed are compounds that modulate the physiological action of the proprotein convertase subtilisin kexin type 9 (PCSK9), and methods of using these modulators to reduce LDL-cholesterol levels and/or for the treatment and/or prevention of cardiovascular disease (CVD), including treatment of hypercholesterolemia.

Novel inhibitors of the high-affinity l-proline transporter as potential therapeutic agents for the treatment of cognitive disorders

The incidence of cognitive disorders such as Alzheimer's disease continues to increase unabated. While cures for such diseases have eluded investigators, progress is being made on alleviating certain symptoms of these diseases. Mouse knockouts of the proline transporter (PROT), a high affinity Na +/Cl--dependent transporter, indicated its potential as a novel therapeutic target for cognition improvement. Herein we report our investigation into a novel class of PROT inhibitors.