CAN-mediated oxidative cleavage of 4-aryl-3,4-dihydroxypiperidines
A CAN-mediated oxidative cleavage of 4-aryl-3,4-dihydroxypiperidines 2Aa-Be to β-amino carbonyl compounds 3Aa-Be and 4Aa-Be in different ratios is described. This facile strategy was also used to synthesize racemic fluoxetine (5).
Chang, Meng-Yang,Lin, Chun-Yu,Pai, Chun-Li
p. 2565 - 2568
(2007/10/03)
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