888723-97-5 Usage
Uses
Used in Pharmaceutical Industry:
(2S,3S,4aR,6R,8aR)-2,3,4a,5,6,8a-Hexahydro-7-iodo-2,3-diMethoxy-2,3,6-triMethyl-1,4-benzodioxin-6-ol is used as an intermediate in the synthesis of (-)-Altenuene (A575740), a toxin isolated from the fungus Alternaria tenuis. This intermediate plays a crucial role in the development of pharmaceuticals targeting specific biological pathways or diseases, potentially leading to the discovery of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 888723-97-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,8,7,2 and 3 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 888723-97:
(8*8)+(7*8)+(6*8)+(5*7)+(4*2)+(3*3)+(2*9)+(1*7)=245
245 % 10 = 5
So 888723-97-5 is a valid CAS Registry Number.
888723-97-5Relevant articles and documents
Total synthesis of altenuene and isoaltenuene
Altemoeller, Martina,Podlech, Joachim,Fenske, Dieter
, p. 1678 - 1684 (2007/10/03)
Total synthesis of altenuene and isoaltenuene, toxins produced by various alternaria fungi, were achieved for the first time in ten steps, starting with quinic acid and commercially available acetal-protected phloroglucinic acid, with the longest linear sequence consisting of seven steps. The key reactions are palladium-catalyzed Suzuki-type couplings between an arene boronate and iodinated cyclohexenes. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.