Synthesis of 3-cyanoflavones and their biological evaluation
The synthesis, using β-bromo-α-ethylthiocinnamonitrile (1) and methyl salicylate (2), of two new series of methyl 2-(2′-cyano-2′-ethylthio-1′-phenylvinyloxy)benzoates (3), precursors of 3-cyanoflavones (4) is reported. Compounds (3) and (4) were checked a
Lassagne, Frederic,Bombarda, Isabelle,Dherbomez, Michel,Sinbandhit, Sourisak,Gaydou, Emil M.
p. 787 - 799
(2007/10/03)
A convenient access to 3-cyanoflavones
Reaction of β-bromo α-alkylthiocinnamonitriles with various substituted methyl salicylates followed by treatment with AlCl 3/PhNO2 provides 3-cyanoflavones.
Lassagne, Frédéric,Pochat, Francis
p. 9283 - 9285
(2007/10/03)
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