89311-53-5 Usage
Uses
Used in Pharmaceutical Industry:
(S)-2-Chlorotryptophan is used as a key component in the development of new drug molecules, leveraging its unique properties to create innovative pharmaceutical agents. Its potential effects on the central nervous system make it a valuable candidate for the treatment of various neurological disorders.
(S)-2-Chlorotryptophan is also used as an anti-inflammatory agent, contributing to the development of medications aimed at reducing inflammation and alleviating pain associated with various conditions.
Used in Chemical Biology:
In the field of chemical biology, (S)-2-Chlorotryptophan serves as a building block for the synthesis of novel compounds with potential therapeutic properties. Its unique structure allows for the creation of new molecules that can be explored for their effects on biological systems and their potential applications in medicine.
Overall, (S)-2-Chlorotryptophan's diverse applications in the pharmaceutical and chemical industries highlight its potential as a versatile and valuable compound for future research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 89311-53-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,3,1 and 1 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 89311-53:
(7*8)+(6*9)+(5*3)+(4*1)+(3*1)+(2*5)+(1*3)=145
145 % 10 = 5
So 89311-53-5 is a valid CAS Registry Number.
89311-53-5Relevant articles and documents
Mechanistic Studies on Tryptophan Lyase (NosL): Identification of Cyanide as a Reaction Product
Bhandari, Dhananjay M.,Fedoseyenko, Dmytro,Begley, Tadhg P.
supporting information, p. 542 - 545 (2018/01/26)
Tryptophan lyase (NosL) catalyzes the formation of 3-methylindole-2-carboxylic acid and 3-methylindole from l-tryptophan. In this paper, we provide evidence supporting a formate radical intermediate and demonstrate that cyanide is a byproduct of the NosL-catalyzed reaction with l-tryptophan. These experiments require a major revision of the NosL mechanism and uncover an unanticipated connection between NosL and HydG, the radical SAM enzyme that forms cyanide and carbon monoxide from tyrosine during the biosynthesis of the metallo-cluster of the [Fe-Fe] hydrogenase.
Synthesis of 2-bromo-L-tryptophan and 2-chloro-L-tryptophan
Phillips,Cohen
, p. 5555 - 5558 (2007/10/02)
Free-radical halogenation of protected L-tryptophan with N-bromosuccinimide or N-chlorosuccinimide leads to the corresponding 2-halo derivative in high yield; enzymatic removal of the blocking groups provides the new amino acid analogues.
