893566-74-0

Basic information

• Product Name: 6-BROMO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER
• Synonyms: 6-BROMO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER;tert-butyl 6-broMo-1,2,3,4-tetrahydroisoquinoline-2-carboxylate;2-Boc-6-bromo-3,4-dihydro-1H-isoquinoline;tert-Butyl 6-bromo-3,4-dihydroisoquinoline-2(1H);6-bromo-2-(tert-butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline;2-Boc-6-bromo-1,2,3,4-tetrahydroisoquinoline
• CAS NO: 893566-74-0
• Molecular Formula: C₁₄H₁₈BrNO₂
• Molecular Weight: 312.21
• Product Categories: CHIRAL CHEMICALS
• Mol File: 893566-74-0.mol

Chemical Properties

• Boiling Point: 374.2 °C at 760 mmHg
• Flash Point: 180.1 °C
• Appearance: /
• Density: 1.353g/cm³
• Vapor Pressure: 8.48E-06mmHg at 25°C
• Refractive Index: 1.559
• Storage Temp.: 2-8°C
• PKA: -1.56±0.20(Predicted)
• CAS DataBase Reference: 6-BROMO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 6-BROMO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER(893566-74-0)
• EPA Substance Registry System: 6-BROMO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER(893566-74-0)

Safety Data

• Hazardous Substances Data: 893566-74-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
6-Bromo-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester is used as a key intermediate in the synthesis of various pharmaceuticals. The tert-butyl ester group provides protection and stability to the carboxylic acid functionality, facilitating the synthesis of complex molecules with desired therapeutic properties.
Used in Organic Chemistry:
In the field of organic chemistry, 6-Bromo-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester serves as a versatile building block for the synthesis of a wide range of organic compounds. Its unique structure allows for various chemical reactions and modifications, enabling the creation of novel molecules with potential applications in various industries.
Used in Medicinal Chemistry:
6-Bromo-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester has been studied for its potential biological activities, making it a promising candidate for drug discovery and development. Its ability to modulate various biological pathways and target specific receptors can lead to the development of new therapeutic agents for the treatment of various diseases and conditions.
Used in Agricultural Chemistry:
6-Bromo-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester may also find applications in agricultural chemistry, where it can be used in the development of new agrochemicals, such as pesticides or herbicides. Its unique structure and potential biological activities can contribute to the creation of more effective and environmentally friendly solutions for crop protection.

InChI:InChI=1/C14H18BrNO2/c1-14(2,3)18-13(17)16-7-6-10-8-12(15)5-4-11(10)9-16/h4-5,8H,6-7,9H2,1-3H3

Upstream product

• 226942-29-6 6-bromo-1,2,3,4-tetrahydroisoquinoline 
• 24424-99-5 di-tert-butyl dicarbonate 
• 75416-51-2 8-bromo-1,2,3,4-tetrahydroisoquinoline 
• 164148-92-9 tert-butyl 6-amino-3,4-dihydroisoquinoline-2(1H)-carboxylate 
• 215798-19-9 6-bromo-1,2,3,4-tetrahydroisoquinoline hydrochloride 
• 34784-05-9 6-bromo-isoquinoline 
• 58971-11-2 2-(3-bromophenyl)ethanamine 
• 31938-07-5 (3-bromophenyl)acetonitrile 

Downstream Products

• 893566-72-8 6-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester 
• 893566-73-9 tert-butyl 8-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 
• 1258440-17-3 2-[(1-methylethyl)oxy]-5-[5-(1,2,3,4-tetrahydro-6-isoquinolinyl)-1,3,4-thiadiazol-2-yl]benzonitrile 
• 1258440-75-3 1,1-dimethylethyl 6-(5-{3-cyano-4-[(1-methylethyl)oxy]phenyl}-1,3,4-thiadiazol-2-yl)-3,4-dihydro-2(1H)-isoquinolinecarboxylate 
• 1258852-58-2 3-[6-(5-{3-cyano-4-[(1-methylethyl)oxy]phenyl}-1,3,4-thiadiazol-2-yl)-3,4-dihydro-2(1H)-isoquinolinyl]propanamide 
• 170097-67-3 2-(tert-butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid 
• 166398-34-1 1,2,3,4-tetrahydroisoquinoline-6-carbonitrile 
• 166398-33-0 tert-butyl 6-cyano-3,4-dihydroisoquinoline-2(1H)-carboxylate 

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