894796-87-3

Basic information

• Product Name: methyl 4-amino-2-(trifluoromethyl)benzoate
• Synonyms: methyl 4-amino-2-(trifluoromethyl)benzoate;4-Amino-2-trifluoromethyl-benzoic acid methyl ester
• CAS NO: 894796-87-3
• Molecular Formula: C₉H₈F₃NO₂
• Molecular Weight: 219.1605296
• Mol File: 894796-87-3.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: methyl 4-amino-2-(trifluoromethyl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-amino-2-(trifluoromethyl)benzoate(894796-87-3)
• EPA Substance Registry System: methyl 4-amino-2-(trifluoromethyl)benzoate(894796-87-3)

Safety Data

• Hazardous Substances Data: 894796-87-3(Hazardous Substances Data)

Upstream product

• 320-37-6 4-nitro-2-(trifluoromethyl)benzoic acid 
• 393-06-6 4-amino-2-(trifluoromethyl)benzoic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 900254-47-9 4-nitro-2-trifluoromethyl benzoic acid methyl ester 

Downstream Products

• 1272527-11-3 4-(3,5-dichloro-4-ethoxybenzamido)-2-(trifluoromethyl)benzoic acid 
• 1613730-42-9 methyl 4-amino-5-methyl-2-(trifluoromethyl)-3-((trimethylsilyl)ethynyl)benzoate 
• 1613730-41-8 methyl 4-amino-3-iodo-5-methyl-2-(trifluoromethyl)benzoate 
• 1613730-40-7 methyl 4-amino-5-methyl-2-(trifluoromethyl)benzoate 
• 1613730-39-4 methyl 4-amino-5-iodo-2-(trifluoromethyl)benzoate 

Relevant articles and documents

INDOLE DERIVATIVE USED AS CRTH2 INHIBITOR

The present application discloses an indole as represented by formula (I) used as a CRTH2 inhibitor, and a pharmaceutically acceptable salt or tautomer of the indole, and an application of same in treating a disease related to a CRTH2 receptor.

UREA DERIVATIVE AND USE THEREFOR

The purpose of the present invention is to provide a compound with inhibitory activity on Discoidin Domain Receptor 1. The present invention provides a urea derivative represented by the formula (I) below or a pharmaceutically acceptable salt thereof.

UREA DERIVATIVE AND USE THEREFOR

The purpose of the present invention is to provide a compound with inhibitory activity on Discoidin Domain Receptor 1. The present invention provides a urea derivative represented by the formula below or a pharmaceutically acceptable salt thereof.

As CRTH2 inhibitor of indole compounds (by machine translation)

The application discloses a formula (I) as shown in CRTH2 inhibitor of indole compound or its pharmaceutically acceptable salt, and their use in the treatment with the CRTH2 receptor-related diseases in the application. (by machine translation)

INDOLE CARBOXAMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS

The invention relates to indole carboxamide derivatives of formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and n are as defined in the description, their preparation and their use as pharmaceutically active compounds.

OXADIAZOLE DERIVATIVES AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS

The present invention relates to novel oxadiazole derivatives as nAChR agonists having pharmacological activity, processes for their preparation, compositions containing them and their use in the treatment of neurological, psychiatric disorders and gastro

2-PHENYL-5-AMINO-1,3,4-OXADIAZOLES AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS

The present invention relates to novel oxadiazole derivatives of formula (1) having pharmacological activity, processes for their preparation, compositions containing them and their use in the treatment of neurological, psychiatric disorders and gastrointestinal disorders through modulation of the nicotinic α7 receptor formula (I).

Cinnamide and hydrocinnamide derivatives with kinase inhibitory activity

The present invention provides novel cinnamide compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.