895519-90-1Relevant articles and documents
Synthesis method of flumatinib
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, (2020/05/11)
The invention discloses a synthesis method of flumatinib mesylate. The flumatinib is prepared by taking 4-methyl-3-(trifluoromethyl) cyanobenzene as an initial raw material through three steps of reactions of bromination, substitution and coupling. The me
A method for preparing fluorine Ma Tini of methanesulfonic acid (by machine translation)
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Paragraph 0021-0024, (2017/03/14)
The invention relates to a method for preparing a sulfonic acid fluorine Ma Tini. The preparation method shortens the reaction time, and the yield is improved and the safety is better, is more suitable for industrial production. (by machine translation)
AMINOPYRIMIDINE COMPOUNDS AND THEIR SALTS, PROCESS FOR PREPARATION AND PHARMACEUTICAL USE THEREOF
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Page/Page column 11, (2008/06/13)
The present invention provides aminopyrimidine compounds of formula (I) and their salts, wherein R1, R2, R3, R4, R5, R6, Q, Z, L, m, n are defined as the description, the methods for preparation thereof, the uses thereof and the pharmaceutical compositions comprising the effective amount of compounds of formula (I). The compounds of formula (I) and their salts can be used as protein kinase inhibitors.