89978-00-7

Basic information

• Product Name: 5-amino-1-(pyrimidin-2-yl)-1H-pyrazole-4-carbonitrile
• Synonyms: 5-Amino-1-(2-pyrimidinyl)pyrazole-4-carbonitrile;1H-Pyrazole-4-carbonitrile, 5-aMino-1-(2-pyriMidinyl)-;5-Amino-1-pyrimidin-2-yl-pyrazole-4-carbonitrile
• CAS NO: 89978-00-7
• Molecular Formula: C₈H₆N₆
• Molecular Weight: 186.17344
• Mol File: 89978-00-7.mol

Chemical Properties

• Boiling Point: 528.674 °C at 760 mmHg
• Flash Point: 273.533 °C
• Appearance: /
• Density: 1.51
• Storage Temp.: 2-8°C
• PKA: -2.06±0.33(Predicted)
• CAS DataBase Reference: 5-amino-1-(pyrimidin-2-yl)-1H-pyrazole-4-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 5-amino-1-(pyrimidin-2-yl)-1H-pyrazole-4-carbonitrile(89978-00-7)
• EPA Substance Registry System: 5-amino-1-(pyrimidin-2-yl)-1H-pyrazole-4-carbonitrile(89978-00-7)

Safety Data

• Hazardous Substances Data: 89978-00-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5-Amino-1-(pyrimidin-2-yl)-1H-pyrazole-4-carbonitrile is used as a building block for the synthesis of drug candidates and bioactive molecules, leveraging its potential biological activities such as anti-inflammatory and anti-cancer properties. It serves as a key component in drug discovery and development processes, contributing to the creation of novel therapeutic agents.
Used in Research Applications:
In research settings, 5-Amino-1-(pyrimidin-2-yl)-1H-pyrazole-4-carbonitrile is utilized as a chemical intermediate for the preparation of various compounds with potential applications in life sciences. Its reactivity and structural features make it a valuable tool for exploring new chemical spaces and understanding molecular interactions.
Used in Agrochemical Development:
5-Amino-1-(pyrimidin-2-yl)-1H-pyrazole-4-carbonitrile is employed in the development of agrochemicals, where its chemical properties can be harnessed to create new pesticides, herbicides, or other agricultural products. Its versatility allows for the design of molecules with specific target activities in crop protection.
Used in Materials Science:
In the field of materials science, 5-Amino-1-(pyrimidin-2-yl)-1H-pyrazole-4-carbonitrile is used for the development of new materials with unique properties. Its chemical structure and reactivity can be exploited to synthesize advanced materials for various applications, such as sensors, catalysts, or functional coatings.

Upstream product

• 7504-94-1 2-pyrimidinylhydrazine 
• 123-06-8 Ethoxymethylenemalononitrile 

Downstream Products

• 1353641-40-3 C₂₂H₁₆N₆O₃ 
• 1229115-36-9 C₂₆H₁₈N₈O₃ 
• 1204702-10-2 C₂₅H₁₆N₈O₂ 
• 1186658-54-7 C₂₄H₁₇N₉O₃ 
• 1186658-67-2 C₂₅H₁₈N₁₀O₃ 
• 1186658-48-9 C₂₃H₁₅N₉O₂ 
• 1186658-42-3 C₂₁H₂₃N₉O₂ 
• 1186658-24-1 C₁₈H₁₀N₁₀O 
• 1186657-93-1 C₁₉H₁₆N₈O₃ 
• 1186659-36-8 C₃₀H₂₀Cl₂N₁₆O₄ 
• 1187086-25-4 C₂₂H₁₇N₁₁ 
• 1187086-19-6 C₂₂H₂₈N₁₀O₂ 
• 1187086-23-2 C₁₂H₁₀N₁₂ 

Relevant articles and documents

AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION

Provided is an azo pigment having excellent coloring characteristics such as high tinctorial strength and hue and having excellent durability such as high resistance to light and ozone, a pigment dispersion containing the azo pigment, and a coloring composition. An azo pigment represented by the following general formula (1), a tautomer of the azo pigment, and a salt or a hydrate thereof: (In the general formula (1), G0 and G1 each independently represents a non-metal atomic group which can form a 5- or 6-membered heterocyclic ring wherein each heterocyclic ring may be unsubstituted or may have a substituent; each heterocyclic ring may be a monocyclic ring or a condensed ring; X represents a hetero atom; n represents an integer of 1 to 4; when n = 2, the compound of formula (1) represents a dimer formed via A or a heterocyclic group represented by G0 or G1;. when n = 3, the compound of formula (1) represents a trimer formed via A and/or a heterocyclic group represented by G0 or C1; when n = 4, the compound of formula (1) represents a tetramer formed via A and/or a heterocyclic group represented by G0 or G1; A represents any one selected from the group of the specific substituents.)

PYRAZOLO-PYRIMIDINE ANILINE COMPOUNDS

Compounds having the formula (I), where all substituents are as defined herein, and pharmaceutically acceptable salts, prodrugs, and solvates thereof, are useful as kinase inhibitors.