899897-20-2

Basic information

• Product Name: 4-Thiazolecarboxylicacid,5-bromo-2-methyl-(9CI)
• Synonyms: 4-Thiazolecarboxylicacid,5-bromo-2-methyl-(9CI);5-bromo-2-methylthiazole-4-carboxylic acid
• CAS NO: 899897-20-2
• Molecular Formula: C₅H₄BrNO₂S
• Molecular Weight: 222.05976
• Product Categories: THIAZOLE
• Mol File: 899897-20-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Thiazolecarboxylicacid,5-bromo-2-methyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Thiazolecarboxylicacid,5-bromo-2-methyl-(9CI)(899897-20-2)
• EPA Substance Registry System: 4-Thiazolecarboxylicacid,5-bromo-2-methyl-(9CI)(899897-20-2)

Safety Data

• Hazardous Substances Data: 899897-20-2(Hazardous Substances Data)

Upstream product

• 6436-59-5 ethyl 2-methylthiazole-4-carboxylate 
• 1047675-70-6 5-bromo-2-methylthioazole-4-carboxylic acid ethyl ester 
• 221558-25-4 5-bromo-4-dichloromethyl-2-methylthiazole 
• 221558-21-0 4-dichloromethyl-2-methylthiazole 
• 221558-28-7 5-bromo-2-methylthiazole-4-carbaldehyde 
• 35272-15-2 2-methylthiazole-4-carboxylic acid 

Downstream Products

• 899897-21-3 methyl 5-bromo-2-methyl-1,3-thiazole-4-carboxylate 

Relevant articles and documents

SUBSTITUTED 2-AZABICYCLO[3.1.1]HEPTANE AND 2-AZABICYCLO[3.2.1]OCTANE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS

There is provided a compound of formula (I), wherein L1 to L3, R1 to R4, X, A and B have meanings given in the description, and pharmaceutically acceptable salts, solvates and prodrugs thereof, which compounds are useful as antagonists of the orexin-1 and orexin-2 receptors or as selective antagonists of the orexin-1 receptor, and thus, in particular, in the treatment or prevention of inter alia substance dependence, addiction, anxiety disorders, panic disorders, binge eating, compulsive disorders, impulse control disorders, cognitive impairment and Alzheimer's disease.

PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES

The invention relates to novel phenethylamide derivatives and their heterocyclic analogues of formula (I), wherein A, B, R1, R2 and R3 are as described in the application, and to the use of such compounds, or of pharmaceut

CYCLOPROPYL PYRROLIDINE OREXIN RECEPTOR ANTAGONISTS

The present invention is directed to cyclopropyl proline bis-amide compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.

Thiazole[4,5-C]pyridine derivatives

The invention relates to compounds of general formula I: wherein R1, R2 and R3 are as defined in the description such compounds are metabotropic glutamate receptor antagonists and are useful in the treatment or prevention of mGluR5 receptor mediated disorders.

Thiazole-4-carboxyamide derivatives

The present invention is concerned with novel thiazole 4-carboxyamide derivatives of the general formula (I) and with methods for the preparation thereof, which compounds are useful as metabotropic glutamate receptor antagonists: wherein R1 to R4 are as defined in the specification.