899897-21-3

Basic information

• Product Name: Methyl 5-bromo-2-methyl-1,3-thiazole-4-carboxylate
• Synonyms: Methyl 5-bromo-2-methyl-1,3-thiazole-4-carboxylate;5-Bromo-4-(methoxycarbonyl)-2-methyl-1,3-thiazole;Methyl 5-bromo-2-methylthiazole-4-carboxylate≥ 95% (HPLC)
• CAS NO: 899897-21-3
• Molecular Formula: C6H6BrNO2S
• Molecular Weight: 236
• Mol File: 899897-21-3.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Methyl 5-bromo-2-methyl-1,3-thiazole-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 5-bromo-2-methyl-1,3-thiazole-4-carboxylate(899897-21-3)
• EPA Substance Registry System: Methyl 5-bromo-2-methyl-1,3-thiazole-4-carboxylate(899897-21-3)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 899897-21-3(Hazardous Substances Data)

Upstream product

• 6436-60-8 methyl 2-methyl-1,3-thiazole-4-carboxylate 
• 67-56-1 methanol 
• 899897-20-2 5-bromo-2-methyl-1,3-thiazole-4-carboxylic acid 

Relevant articles and documents

N-SUBSTITUTED-3,4-(FUSED 5-RING)-5-PHENYL-PYRROLIDINE-2-ONE COMPOUNDS AS INHIBITORS OF ISOQC AND/OR QC ENZYME

The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain N-substituted-3,4-(fused 5-ring)-5-phenyl-pyrrolidin-2-one compounds (also referred to herein as "FRPPO compounds"), that, inter alia, inhibit glutaminyl-peptide cyclotransferase-like (isoQC) enzyme and/or glutaminyl-peptide cyclotransferase (QC) enzyme (e.g., inhibit or reduce or block the activity or function of isoQC and/or QC enzyme). The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit isoQC and/or QC enzyme; to treat disorders that are ameliorated by the inhibition of isoQC and/or QC enzyme; to treat cancer, atherosclerosis, fibrotic diseases, infectious diseases, Alzheimer's disease, etc.

Thiazole-4-carboxyamide derivatives

The present invention is concerned with novel thiazole 4-carboxyamide derivatives of the general formula (I) and with methods for the preparation thereof, which compounds are useful as metabotropic glutamate receptor antagonists: wherein R1 to R4 are as defined in the specification.