902835-93-2 Usage
Uses
Used in Organic Synthesis:
2-(BOC-aMino)-3-hydroxypyridine is used as a building block for the synthesis of various organic compounds. Its presence of a BOC protecting group and a hydroxyl group allows for selective reactions and the formation of diverse chemical structures.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2-(BOC-aMino)-3-hydroxypyridine is used as a key intermediate in the development of biologically active compounds and pharmaceutical drugs. Its unique structure and functional groups contribute to the design and synthesis of novel therapeutic agents.
Used in Medicinal Chemistry:
2-(BOC-aMino)-3-hydroxypyridine is employed as a versatile intermediate in medicinal chemistry for the synthesis of potential drug candidates. The BOC protecting group can be selectively removed, facilitating the introduction of various functional groups and the exploration of structure-activity relationships.
Used in Drug Development:
In drug development, 2-(BOC-aMino)-3-hydroxypyridine is utilized as a precursor in the synthesis of new pharmaceutical agents. Its reactivity and the ability to remove the BOC protecting group under mild conditions make it a valuable component in the creation of innovative drug molecules.
Overall, 2-(BOC-aMino)-3-hydroxypyridine is a valuable chemical entity with broad applications in organic synthesis, pharmaceutical research, medicinal chemistry, and drug development, owing to its unique structural features and the versatility of its BOC protecting group.
Check Digit Verification of cas no
The CAS Registry Mumber 902835-93-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,0,2,8,3 and 5 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 902835-93:
(8*9)+(7*0)+(6*2)+(5*8)+(4*3)+(3*5)+(2*9)+(1*3)=172
172 % 10 = 2
So 902835-93-2 is a valid CAS Registry Number.
902835-93-2Relevant articles and documents
Guanidine hydrochloride as an organocatalyst for N-Boc protection of amino groups
Jahani, Fatemeh,Tajbakhsh, Mahmood,Golchoubian, Hamid,Khaksar, Samad
supporting information; experimental part, p. 1260 - 1264 (2011/04/15)
A simple and efficient method for the chemoselective N-Boc protection of the amine moiety in a variety of compounds is described using di-tert-butyl dicarbonate and guanidine hydrochloride as an organocatalyst in ethanol at 35-40°C. Selective mono-N-Boc protection of diamines and chemoselective protection of hydroxylamines without formation of any side products is achieved. Amino acids and peptides are N-Boc protected efficiently in excellent yields under convenient reaction conditions.
An efficient and highly chemoselective N-Boc protection of amines, amino acids, and peptides under heterogeneous conditions
Jahani, Fatemeh,Tajbakhsh, Mahmood,Khaksar, Samad,Azizi, Mohamad Reza
experimental part, p. 1035 - 1043 (2012/07/27)
A simple and efficient procedure for chemoselective mono-N-Boc protection of various structurally diverse amines, amino acids, and peptides with di-tert-butyl dicarbonate using Amberlyst-15 as catalyst in ethanol is described. The catalyst can be readily separated from the reaction products with simple filtration and recovered for direct reuse. No competitive side-reactions such as formation of isocyanate, urea, oxazolidinone, and N,N-di-Boc derivatives were observed.
