2-(BOC-aMino)-3-hydroxypyridine

Base Information

• Chemical Name: 2-(BOC-aMino)-3-hydroxypyridine
• CAS No.: 902835-93-2
• Molecular Formula: C10H14N2O3
• Molecular Weight: 210.22976
• Mol file: 902835-93-2.mol

Synonyms:2-(BOC-aMino)-3-hydroxypyridine;N-(3-Hydroxy-2-pyridinyl)carbamic acid 1,1-dimethylethyl ester;tert-Butyl (3-hydroxypyridin-2-yl)carbamate;Carbamic acid, N-(3-hydroxy-2-pyridinyl)-, 1,1-dimethylethyl ester

Chemical Property of 2-(BOC-aMino)-3-hydroxypyridine

Chemical Property:

• Melting Point: 129-132℃
• PSA: 71.45000
• LogP: 2.20720
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

2-(Boc-Amino)-3-hydroxypyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(BOC-aMino)-3-hydroxypyridine

There total 1 articles about 2-(BOC-aMino)-3-hydroxypyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-amino-3-hydroxypyridine (16867-03-1) + di-tert-butyl dicarbonate (24424-99-5) → N-(tert-butoxycarbonyl)-2-amino-3-hydroxypyridine (902835-93-2)

Guidance literature:

With guanidine hydrochloride; In ethanol; at 35 - 40 ℃; for 2.5h;

DOI:10.1016/j.tetlet.2011.01.023

upstream raw materials:

2-amino-3-hydroxypyridine

di-tert-butyl dicarbonate