903513-62-2

Basic information

• Product Name: (2-AMINO-4-PYRIDYL)BORONIC ACID
• Synonyms: (2-AMINO-4-PYRIDYL)BORONIC ACID;2-aminopyridin-4-ylboronic acid;2-Aminopyridine-4-boronic acid;2-aMino-4-pyridinyl boronic acid;(2-Aminopyridin-4-yl)
• CAS NO: 903513-62-2
• Molecular Formula: C₅H₇BN₂O₂
• Molecular Weight: 137.93
• EINECS: 1533716-785-6
• Product Categories: 6
• Mol File: 903513-62-2.mol

Chemical Properties

• Boiling Point: 411.7±55.0 °C(Predicted)
• Appearance: /
• Density: 1.33±0.1 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Sealed in dry,Store in freezer, under -20°C
• PKA: 5.74±0.10(Predicted)
• CAS DataBase Reference: (2-AMINO-4-PYRIDYL)BORONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (2-AMINO-4-PYRIDYL)BORONIC ACID(903513-62-2)
• EPA Substance Registry System: (2-AMINO-4-PYRIDYL)BORONIC ACID(903513-62-2)

Safety Data

• Hazardous Substances Data: 903513-62-2(Hazardous Substances Data)

Usage

Uses

Used in Chemical Research:
(2-Amino-4-Pyridyl)boronic Acid is used as a research chemical for its unique properties and reactivity in various chemical reactions. Its affinity for diols allows it to be employed in the synthesis of complex organic molecules and the development of new chemical processes.
Used in Pharmaceutical Industry:
(2-Amino-4-Pyridyl)boronic Acid is used as a building block or intermediate in the synthesis of pharmaceutical compounds. Its unique structure and reactivity can be exploited to create new drugs with potential therapeutic applications.
Used in Material Science:
(2-Amino-4-Pyridyl)boronic Acid is used as a component in the development of new materials with specific properties. Its ability to form stable bonds with other molecules can contribute to the creation of advanced materials for various applications, such as sensors, catalysts, or coatings.
Used in Analytical Chemistry:
(2-Amino-4-Pyridyl)boronic Acid can be used as a reagent or analytical tool in various analytical techniques. Its affinity for diols makes it suitable for the detection and quantification of specific compounds in complex samples.

Upstream product

• 84249-14-9 2-amino-4-bromopyridine 
• 73183-34-3 bis(pinacol)diborane 
• 19798-80-2 2-Amino-4-chloropyridine 

Downstream Products

• 1368227-63-7 4-(3-aminophenyl)pyridin-2-amine 
• 1240523-34-5 C₂₅H₂₈N₄O₃ 
• 1240523-35-6 C₂₄H₂₃N₅OS 
• 1258311-32-8 C₂₃H₂₄N₆O₂ 
• 1150542-85-0 2-(2-aminopyridin-4-yl)-3-(3-chloro-4-fluorophenyl)-1H-pyrrolo[3,2-b]pyridine-5-carbonitrile 

Relevant articles and documents

REV-ERB AGONISTS FOR THE TREATMENT OF TH17-MEDIATED INFLAMMATORY DISORDERS

The present disclosure provides compounds of Formula IA and Formula IB and their pharmaceutical compositions as selective agonists of REV-ERB-α: where R1, R2, R3, R4, R5, RX1, RX2, nA, nB, X, Y, and Z are described herein. The compounds are useful in various methods and uses, such as in the treatment of diseases including hyperglycemia, dyslipidemia, atherosclerosis, and autoimmune and inflammatory disorders or diseases, and as cancer therapeutics, such as for the treatment of glioblastoma, hepatocellular carcinoma, and colorectal cancer, and for immune-oncology purposes.

FARNESOID X RECEPTOR AGONISTS AND USES THEREOF

Described herein are compounds that are farnesoid X receptor agonists, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with farnesoid X receptor activity.

FARNESOID X RECEPTOR AGONISTS AND USES THEREOF

Described herein are compounds that are farnesoid X receptor agonists, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with farnesoid X receptor activity.

6,7-DIHYDROPYRAZOLO[1,5-a]PYRAZIN-4(5H)-ONE COMPOUNDS AND THEIR USE AS NEGATIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS

The present invention relates to novel 6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one derivatives of Formula (I) as negative allosteric modulators (NAMs) of the metabotropic glutamate receptor subtype 2 ("mGluR2"). The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention or treatment of disorders in which the mGluR2 subtype of metabotropic receptors is involved, especially CNS disorders.

Syntheses of novel 2,3-diaryl-substituted 5-cyano-4-azaindoles exhibiting c-Met inhibition activity

Herein we report the syntheses of 2,3-diaryl-substituted pyrrolo[3,2-b]pyridine-5-carbonitriles via a one-pot 5-endo-dig-cyclization/protection reaction followed by palladium catalyzed arylation. In addition, a complementary synthesis route employing Laro