90539-80-3

Basic information

• Product Name: 1-benzoyl-3-cyanoindole
• Synonyms: 1-benzoyl-3-cyanoindole
• CAS NO: 90539-80-3
• Molecular Formula: C₁₆H₁₀N₂O
• Molecular Weight: 246
• Mol File: 90539-80-3.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-benzoyl-3-cyanoindole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzoyl-3-cyanoindole(90539-80-3)
• EPA Substance Registry System: 1-benzoyl-3-cyanoindole(90539-80-3)

Safety Data

• Hazardous Substances Data: 90539-80-3(Hazardous Substances Data)

Usage

Benzoylated derivative

3-cyanoindole 1-benzoyl-3-cyanoindole is derived from 3-cyanoindole by attaching a benzoyl group, making it a modified version of the original compound.

Versatile building block

Organic synthesis The compound serves as a useful intermediate in organic synthesis, allowing for the creation of various complex organic molecules.

Potential applications

Pharmaceutical and agrochemical industries Due to its diverse pharmacological activities, 1-benzoyl-3-cyanoindole can be used in the development of new drugs and agrochemicals.

Pharmacological activities

Anti-inflammatory, anti-cancer, and antimicrobial properties The compound exhibits a range of biological activities, making it a promising candidate for therapeutic and protective applications.

Fluorescent probe

Protein kinase C activity detection 1-benzoyl-3-cyanoindole has been studied for its potential use as a fluorescent probe in biochemical research, specifically for monitoring protein kinase C activity.

Synthesis of complex organic molecules

Novel drug candidates and agrochemicals The compound's ability to serve as a building block in organic synthesis contributes to the development of new and potentially innovative pharmaceutical and agrochemical products.

Upstream product

• 127280-08-4 N-Benzoylindole-3-carboxaldehyde N,N-dimethylhydrazone 
• 5457-28-3 3-cyano-1H-indole 
• 98-88-4 benzoyl chloride 

Downstream Products

• 90540-04-8 methyl 3-benzoyl-7b-cyano-1,2,2a,7b-tetrahydro-3H-cyclobutindole-2-carboxylate 
• 90540-03-7 methyl exo-3-benzoyl-7b-cyano-1,2,2a,7b-tetrahydro-3H-cyclobutindole-1-carboxylate 
• 90540-03-7 methyl endo-3-benzoyl-7b-cyano-1,2,2a,7b-tetrahydro-3H-cyclobutindole-1-carboxylate 
• 90539-87-0 exo-1-acetoxy-3-benzoyl-7b-cyano-1,2,2a,7b-tetrahydro-3H-cyclobutindole 
• 90539-87-0 endo-1-acetoxy-3-benzoyl-7b-cyano-1,2,2a,7b-tetrahydro-3H-cyclobutindole 

Relevant articles and documents

On attempted Diels-Alder reaction of 1-ethoxycarbonylindole-3-carboxaldehyde N,N-dimethylhydrazone

The reaction of 1-ethoxycarbonylindole-3-carboxaldehyde N,N-dimethylhydrazine with five dienophiles has been studied, and the first use of this new azadiene in a Diels-Alder reaction with N-methylmaleimide has been achieved leading to a new synthesis of a

Study of the reactions of four indolic 1-azadienes with a few enoic, ynoic, and azo dienophiles

Four indolic 1-azadienes (1a-c, 2) underwent Diels-Alder reaction, dienophile-catalysed addition-elimination reaction, Michael reaction or hydrolysis with three enoic, two ynoic and one azo dienophiles, leading to a γ-carboline, various 3-cyanoindoles, 3-formylindole and several nitrones.

Manganese(III) acetate initiated oxidative free radical reaction between benzoylindoles and dimethyl malonate

A free radical reaction between benzoylindoles and dimethyl malonate initiated by manganese(III) acetate is described. This free radical reaction provides a new method for the synthesis of indolo[1,2-b]isoquinolines and benzo[b]carbazoles. With meta subst

Regio- and Stereo-chemical Aspects of Photocycloaddition Between 1-Benzoylindoles and Olefins

The regio- and stereo-selectivities in the photocycloaddition of a series of 1-benzoylindoles with vinyl acetate and methyl acrylate have been investigated.With some exceptions, the 1-benzoylindoles gave exclusively or predominatly the corresponding 1-acetoxy-3-benzoyl and 3-benzoyl-1-methoxycarbonyl-1,2,2a,7b-tetrahydro-3H-cyclobutindoles as mixtures of stereoisomers.