90764-56-0

Basic information

• Product Name: AIAH
• Synonyms: (+)-s-2-amino-5-iodoacetamidopentanoicacid;2-aipa;2-amino-6-iodoacetamidohexanoicacid;n(sup6)-(iodoacetyl)-l-lysin;n(sup6)-(iodoacetyl)-l-lysine;(S)-(+)-AMINO-6-IODOACETAMIDOHEXANOIC ACID;AIAH;(2S)-(+)-AMINO-6-IODOACETAMIDOHEXANOIC ACID
• CAS NO: 90764-56-0
• Molecular Formula: C8H15IN2O3
• Molecular Weight: 314.12
• Mol File: 90764-56-0.mol

Chemical Properties

• Boiling Point: 500 °C at 760 mmHg
• Flash Point: 256.2 °C
• Appearance: /
• Density: 1.706 g/cm³
• Vapor Pressure: 2.35E-11mmHg at 25°C
• Refractive Index: 1.574
• CAS DataBase Reference: AIAH(CAS DataBase Reference)
• NIST Chemistry Reference: AIAH(90764-56-0)
• EPA Substance Registry System: AIAH(90764-56-0)

Safety Data

• Hazardous Substances Data: 90764-56-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
AIAH is used as a research compound for studying the role of ornithine decarboxylase and arginase in various biological processes and diseases. Its inhibitory properties make it a valuable tool in understanding the mechanisms of these enzymes and their potential as therapeutic targets.
Used in Cancer Research:
AIAH is used as a potential therapeutic agent in cancer research, as ornithine decarboxylase is often overexpressed in various types of cancer. By inhibiting this enzyme, AIAH may help to reduce tumor growth and progression.
Used in Neurological Disorders Research:
AIAH is used as a research tool in the study of neurological disorders, as arginase inhibition has been implicated in the regulation of nitric oxide synthesis and may have potential therapeutic effects in conditions such as neurodegeneration and stroke.
Used in Wound Healing and Tissue Repair:
AIAH is used as a research compound in the investigation of wound healing and tissue repair processes, as ornithine decarboxylase plays a role in cell proliferation and tissue regeneration. Inhibiting this enzyme with AIAH may provide insights into the mechanisms of wound healing and potential therapeutic approaches.

InChI:InChI=1/C8H15IN2O3/c9-5-7(12)11-4-2-1-3-6(10)8(13)14/h6H,1-5,10H2,(H,11,12)(H,13,14)/t6-/m0/s1

Upstream product

• 31252-85-4 Iodoacetic acid 4-nitrophenyl ester 
• 657-27-2 L-Lysine hydrochloride 

Relevant articles and documents

Regioselective synthesis of (+)-S-2-amino-5-iodoacetamidopentanoic and (+)-S-2-amino-6-iodoacetamidohexanoic acids

Mild reaction conditions were developed for the preparation of the active-site-directed irreversible enzyme inhibitors (+)-S-2-amino-5-iodoacetamido-pentanoic acid and (+)-S-2-amino-6-iodoacetamido-hexanoic acid.