657-27-2

Basic information

• Product Name: L-Lysine hydrochloride
• Synonyms: darvyl;lyamine;monohydrochloride,l-lysin;(S)-(+)-LYSINE HYDROCHLORIDE;L(+)-2,6-DIAMINOHEXANOIC ACID, HYDROCHLORIDE;L-(+)-2,6-DIAMINO-N-CAPROIC ACID MONOHYDROCHLORIDE;L(+)-2,6-DIAMINOCAPROIC ACID, HYDROCHLORIDE;L-LYS HCL
• CAS NO: 657-27-2
• Molecular Formula: C₆H₁₅N₂O₂*Cl
• Molecular Weight: 182.65
• EINECS: 211-519-9
• Product Categories: chiral;Lysine [Lys, K];Amino Acids and Derivatives;alpha-Amino Acids;Amino Acids;Biochemistry;for Resolution of Acids;Optical Resolution;Synthetic Organic Chemistry;L-Amino Acids;Amino hydrochloride;amino
• Mol File: 657-27-2.mol
• Article Data: 8

Chemical Properties

• Melting Point: 263 °C (dec.)(lit.)
• Boiling Point: 311.5oC at 760 mmHg
• Flash Point: 142.2oC
• Appearance: White to Off-white/powder
• Density: 1.28 g/cm3 (20℃)
• Vapor Pressure: 0.000123mmHg at 25°C
• Storage Temp.: 2-8°C
• Solubility: H2O: 100 mg/mL
• Water Solubility: 65 g/100 mL (20 ºC)
• Stability: Stable. Incompatible with strong oxidizing agents.
• Merck: 14,5636
• BRN: 3563889
• CAS DataBase Reference: L-Lysine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: L-Lysine hydrochloride(657-27-2)
• EPA Substance Registry System: L-Lysine hydrochloride(657-27-2)

Safety Data

• Hazard Codes: Xi
• Statements: 34-36/37/38
• Safety Statements: 26-36/37/39-45-24/25
• RIDADR: UN 1789 8/PG 3
• WGK Germany: 2
• RTECS: OL5650000
• F: 10
• TSCA: Yes
• Hazardous Substances Data: 657-27-2(Hazardous Substances Data)

Usage

Synthesis

L-Lysine hydrochloride can be synthesisied by microbial fermentation to give?crude L-Lysine , and then purified and synthesized by crystallization in hydrochloric acid.

Description

A white or nearly white, practically odorless, free-flowing, crys talline powder. It is freely soluble in water, but is almost insoluble in alcohol and in ether. It melts at about 260°C with decomposition.

Chemical Properties

White crystalline powder

Uses

amino acid, nutrient

Uses

L-(+)-Lysine Monohydrochloride

Uses

L-Lysine monohydrochloride is widely used as nutritional supplements in food and beverage industries. It can also be used in animal feed as source of L-Lysine.? L-Lysine Monohydrochloride can be used in a wide variety of industries including: food production, beverage, pharmaceutical, agriculture/animal feed, and various other industries.

Definition

ChEBI: The hydrochloride salt of L-lysine

Biochem/physiol Actions

L-lysine is an essential amino acid in animals and humans. L-Lysine is necessary for protein synthesis in the body and proper growth. L-lysine lowers the cholesterol level by producing carnitine. L-lysine aids in calcium, zinc and iron absorption. Athletes take L-lysine as a supplement for lean mass building and for proper muscle and bone health. L-lysine competes with arginine during viral replication and reduces herpes simplex virus infection. L-lysine supplementation reduces chronic anxiety in human. Lysine reduces viscosity of serum albumin solution for injections.

Safety Profile

iWdly toxic by ingestion. When heated to decomposition it emits very toxic fumes of HCl and NOx.

Purification Methods

Likely impurities are arginine, D-lysine, 2,6-diaminoheptanedioic acid and glutamic acid. Crystallise the monohydrochloride from water at pH 4-6 by adding 4 volumes of EtOH. At above 60% relative humidity it forms a dihydrate. [Birhbaum et al. J Biol Chem 194 455, 468 1952, Kearley & Ingersoll J Am Chem Soc 73 5783 1951, Beilstein 4 IV 2717.]

InChI:InChI=1/C6H14N2O2.ClH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H

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Downstream Products

• 2483-46-7 (S)-2,6-Bis-tert-butoxycarbonylaminohexanoic acid 

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