909391-56-6

Basic information

• Product Name: DIMETHYL-[3-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-BENZYL]-AMINE
• Synonyms: DIMETHYL-[3-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-BENZYL]-AMINE;3-(N,N-Dimethylaminomethyl)phenylboronic acid, pinacol ester;3-Dimethylaminomethylphenylboronic acid pinacol ester;Dimethyl[[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl]amine;N,N-diMethyl-1-(3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)phenyl)MethanaMine;3-Dimethylaminomethylphenylboronic acid pinacol ester Dimethyl[[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl]amine;N,N-dimethyl(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanamine;N,N-Dimethyl-1-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methylamine
• CAS NO: 909391-56-6
• Molecular Formula: C₁₅H₂₄BNO₂
• Molecular Weight: 261.18
• Mol File: 909391-56-6.mol

Chemical Properties

• Boiling Point: 340.8±25.0 °C(Predicted)
• Appearance: /
• Density: 1.00
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 8.78±0.28(Predicted)
• CAS DataBase Reference: DIMETHYL-[3-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-BENZYL]-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: DIMETHYL-[3-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-BENZYL]-AMINE(909391-56-6)
• EPA Substance Registry System: DIMETHYL-[3-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-BENZYL]-AMINE(909391-56-6)

Safety Data

• Hazardous Substances Data: 909391-56-6(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
DIMETHYL-[3-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-BENZYL]-AMINE is used as a synthetic intermediate for the preparation of various organic compounds due to its dioxaborolane moiety, which is commonly utilized in cross-coupling reactions.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, DIMETHYL-[3-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-BENZYL]-AMINE is used as a building block for the development of new drugs, leveraging its unique chemical structure to create molecules with specific therapeutic properties.
Used in Materials Science:
DIMETHYL-[3-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-BENZYL]-AMINE is used as a component in the synthesis of advanced materials, potentially contributing to the development of new polymers, coatings, or other materials with specialized properties.

Upstream product

• 124-40-3 dimethyl amine 
• 214360-74-4 2-(3-(bromomethyl)phenyl)-4,4,5,5,-tetramethyl-1,3,2-dioxaborolane 
• 103-83-3 N,N'-dimethylbenzylamine 
• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 

Relevant articles and documents

Iron-catalyzed C-H borylation of arenes

Well-defined iron bis(diphosphine) complexes are active catalysts for the dehydrogenative C-H borylation of aromatic and heteroaromatic derivatives with pinacolborane. The corresponding borylated compounds were isolated in moderate to good yields (25-73%) with a 5 mol% catalyst loading under UV irradiation (350 nm) at room temperature. Stoichiometric reactivity studies and isolation of an original trans-hydrido(boryl)iron complex, Fe(H)(Bpin)(dmpe)2, allowed us to propose a mechanism showing the role of some key catalytic species.

2- (4-0X0-4H-QUINAZ0LIN-3-YL) ACETAMIDES AND THEIR USE AS VASOPRESSIN V3 ANTAGONISTS

The present invention relates to 2-(4-oxo4H-quinazolin-3-yl)acetamicle derivatives of formula (I), and to their use as vasopressin V3 antagonists, particularly for the treatment of depression.